Plasma Levels, Half-lives of Coagulation Factors
| Factor | Level | Half-life | | (μM) | (h) | | Fibrinogen | 7.6 | 72-120 | | Prothrombin | 1.4 | 72 | | Factor V | 0.03 | 36 | | Factor VII | 0.01 | 3-6 | | Factor VIII | 0.00003 | 12 | | Factor IX | 0.09 | 24 | | Factor X | 0.17 | 40 | | Factor XI | 0.03 | 80 | | Factor XIII | 0.03 | 120-200 | | vWF | 0.03 | 10-24 | | Protein C | 0.08 | 10 | | Protein S | 0.14 | 42 | | Antithrombin | 2.6 | 48-72 |
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Modified from Tanaka KA, Key NS, Levy JH. Blood coagulation: hemostasis and thrombin regulation. Anesth Analg. 2009;108:1433-1446.