Elimination of Inhaled Anesthetics is Defined As the Ratio of the End-Tidal Anesthetic Concentration (Fa) to the Fa Immediately Before the Beginning of Elimination (Fao)

Elimination of Inhaled Anesthetics is Defined As the Ratio of the End-Tidal Anesthetic Concentration (Fa) to the Fa Immediately Before the Beginning of Elimination (Fao) The Rate of Decrease (Awakening from Anesthesia) in the Fa/Fao is Most Rapid With the Anesthetics that are Least Soluble in Blood (Nitrous Oxide, Desflurane, Sevoflurane).

(From Yasuda N, Lockhart SH, Eger EI II, et al. Comparison of kinetics of sevoflurane and isoflurane in humans. Anesth Analg. 1991;72:316-324, with permission.)

Elimination of inhaled anesthetics is defined as the ratio of the end-tidal anesthetic concentration (FA) to the FA immediately before the beginning of elimination (FAO). The rate of decrease (awakening from anesthesia) in the FA/FAO is most rapid with the anesthetics that are least soluble in blood (nitrous oxide, desflurane, sevoflurane).

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Figure 4-8