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Figure 5-5

The Principal Metabolite of Midazolam is 1-Hydroxymidazolam

(From Reves JG, Fragen RJ, Vinik HR, et al. Midazolam: pharmacology and uses. Anesthesiology. 1985;62:310-324, with permission.)

A lesser amount of midazolam is metabolized to 4-hydroxymidazolam.