The Role of the Renin-Angiotensin System in the Maintenance of Effective Circulating Volume

(From Lote CJ, Harper L, Savage COS. Mechanisms of acute renal failure. Br J Anaesth. 1996;77:82-89, with permission.)

Renal blood flow and glomerular filtration rate, but not urine output, are autoregulated between a mean arterial pressure of approximately 60 and 160 mm Hg.