Comparative Pharmacology of Benzodiazepines
| Equivalent Dose (mg) | Volume of Distribution(L/kg) | Protein Binding (%) | Clearance (mL/kg/min) | Elimination Half-Time (h) | | Midazolam | 0.15-0.3 | 1.0-1.5 | 96-98 | 6-8 | 1-4 | | Diazepam | 0.3-0.5 | 1.0-1.5 | 96-98 | 0.2-0.5 | 1-37 | | Lorazepam | 0.05 | 0.8-1.3 | 96-98 | 0.7-1.0 | 10-20 |
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