DDx ⬇
- Raynaud's disease (idiopathic)
- Raynaud's phenomenon: associated with conditions listed below
- Livedo reticularis
- Acrocyanosis
- Erythromelalgia
Associated conditions
- Autoimmune disease, eg, scleroderma, systemic lupus erythematosus, dermatomyositis, rheumatoid arthritis
- Arterial occlusive disease, eg, atherosclerosis, emboli, thromboangiitis obliterans (Buergers disease)
- Cryoglobulinemia, myeloproliferative disorders, multiple myeloma, macroglobulinemia
- Thoracic outlet syndrome
- Carpal tunnel syndrome
- Myxedema (hypothyroidism)
- Chemotherapeutic agents, ergotamine, nicotine, estrogen, sympathomimetics, cocaine, polyvinyl chloride
- Frostbite
- Hand-arm vibration syndrome or hypothenar hammer (jackhammer) syndrome
Related DDx ⬆