COAGULATION SCREENING TESTS: APTT, PT, TCT

INTRINSIC FACTOR DEFECTS

Factor VIII (Hemophilia A)
Factor IX (Hemophilia B)

Contact Deficiencies
Factor XI
Factor XII (Hageman trait)
Prekallikrein
HMW Kininogen

EXTRINSIC FACTOR DEFECTS

Factor VII deficiency

COMMON PATHWAY OR COMBINED DEFECTS

Common Pathway
Factor II (Thrombin)
Factor V
Factor X

Combined Deficiency
Vitamin K dependent factors: Factor II, VII, IX, X

FIBRINOGEN AND COMBINED DEFECTS

Fibrinogen
Severe deficiency
High concentration inhibitors

Combined Deficiency
Deficiency of fibrinogen and intrinsic, extrinsic, and common pathway factors

End

APTT: LONG
PT, TCT: NORMAL

PT: LONG
APTT, TCT: NORMAL

APTT& PT: LONG TCT NORMAL

ALL TESTS LONG