section name header

Basics

Basics

Overview

  • Trichiasis-when hair arising from normal skin contacts the corneal or conjunctival surfaces.
  • Distichiasis-when extra lashes emerge from or near the meibomian gland orifices on the lid margin; these hairs may or may not contact the cornea.
  • Ectopic cilia-single or multiple hairs that arise from the palpebral conjunctival surface several millimeters from the lid margin, most commonly near the middle of the superior lid. Occasionally ectopic cilia can arise on the back of the third eyelid.

Signalment

  • Common in dog; rare in cat.
  • Most common in young dogs.
  • Any breed may be affected.
  • Trichiasis: (a) facial fold trichiasis-common in brachycephalic breeds with prominent facial folds (e.g. Pekingese, pug and bulldog); (b) eyelid agenesis-sporadic. Usually bilateral at lateral aspect of upper lids in cats. Often associated with concurrent intraocular abnormalities; (c) entropion-conformational entropion is common in young dogs in predisposed breeds (Shar Pei, retriever, Chow Chow, among many others). Can be associated with blepharospasm (spastic entropion), scarring (cicatricial entropion), or enophthalmos; occasionally seen in cats.
  • Distichiasis-predisposed breeds include cocker spaniel, American water spaniel, English bulldog, beagle, flat-coated retriever and dachshund. Dogs with distichiasis are also prone to have ectopic cilia. Rare in cats.
  • Ectopic cilia-predisposed breeds include Pekingese, shih tzu and English bulldog.

Signs

Facial-Fold Trichiasis

  • Epiphora.
  • Pigmentary keratitis (especially nasally).
  • Often associated with lagophthalmos.
  • Occasional blepharospasm, especially if ulcerative keratitis is present.

Eyelid Agenesis

  • Keratitis, including ulcerative keratitis
  • Lagophthalmos
  • Blepharospasm

Entropion

  • Blepharospasm
  • Epiphora
  • Keratitis, including ulcerative keratitis

Distichiasis

  • Usually asymptomatic.
  • Stiff, stout cilia contacting the cornea-may note blepharospasm, epiphora, pigmentary and ulcerative keratitis.

Ectopic Cilia

  • Severe blepharospasm.
  • Epiphora.
  • Superficial corneal ulcers with a rounded appearance (corresponding to lid movement) on the superior cornea; resistant to healing or recurrent until the underlying problem is corrected.

Causes & Risk Factors

Usually related to facial conformation or breed predisposition, or is idiopathic.

Diagnosis

Diagnosis

Differential Diagnosis

  • Secondary to other adnexal abnormalities (e.g., entropion, eyelid agenesis).
  • Keratoconjunctivitis sicca.
  • Conjunctival foreign body.
  • Infectious conjunctivitis.
  • Diagnosis based on direct observation of abnormal cilia and lid conformation.

CBC/Biochemistry/Urinalysis

N/A

Other Laboratory Tests

N/A

Imaging

N/A

Diagnostic Procedures

N/A

Treatment

Treatment

Trichiasis

  • May be managed conservatively in some patients by protecting the cornea with topical lubricating ointments.
  • Clipping the hair on facial folds may cause these hairs to become stiffer and more irritating.
  • Surgical correction of adnexal abnormalities.
  • May resect facial folds.
  • Medial canthoplasty-often an effective procedure for nasal trichiasis; also eliminates lagophthalmos and medial entropion.
  • Entropion repair.
  • Repair of eyelid agenesis or treat distichiasis as noted below.
  • Treat underlying cause (e.g., spastic entropion, enophthalmia).

Distichiasis

  • Usually asymptomatic and requires no treatment.
  • Symptomatic-may treat surgically by cryoepilation, electroepilation, transconjunctival electrocautery and periodic manual epilation.
  • Lid-splitting and partial tarsal plate excision techniques-avoid; postoperative scarring may predispose patient to cicatricial entropion and impaired lid function.

Ectopic Cilia

  • May be treated surgically-en-bloc resection of the cilia and associated meibomian gland.
  • Cryotherapy-may be used as the sole treatment or as an adjunct after surgical resection.
  • May develop ectopic cilia at other locations.
  • Recheck patient if clinical signs recur.

Medications

Medications

Drug(s)

  • Rarely indicated.
  • Lubricant ointments-sometimes valuable to soften cilia and lessen irritation before surgical correction.
  • Soft contact lens-sometimes can use temporarily to relieve clinical signs before surgical correction.
  • Topical antibiotics-perioperative; recommended for patients undergoing surgery to minimize conjunctival flora in the surgical sites.

Contraindications/Possible Interactions

N/A

Follow-Up

Follow-Up

Miscellaneous

Miscellaneous

Suggested Reading

Gelatt KN, Gilger BC, Kern TJ. Veterinary Ophthalmology, 5th ed. Ames, IA: Wiley-Blackwell, 2013, pp. 832893.

Genetics Committee of the American College of Veterinary Ophthalmologists. Ocular disorders presumed to be inherited in purebred dogs. 2013.

Maggs DJ, Miller PE, Ofri R. Eyelids. In: Slatter's Fundamentals of Veterinary Ophthalmology, 5th ed. St. Louis, MO: Saunders, 2013, pp. 110139.

Petersen-Jones S, Crispin S. The eyelids and nictitating membrane. In: BSAVA Small Animal Ophthalmology, 2nd ed. Gloucester: BSAVA, 2002, pp. 78104.

Author Filipe Espinheira

Consulting Editor Paul E. Miller

Acknowledgment The author and editors acknowledge the prior contribution of Erin S. Champagne.