Cervical Cytology Screening Test

Repeat Cytology in 4-6 mo

Repeat Cytology in 12 mo

Colposcopy Normal?

Yes

No

Routine Screening

Repeat Cytology in 12 mo

Cytology in 6 and 12 mo or HPV DNA Testing in 12 mo

Routine Screening

Repeat Colposcopy

Routine Screening

Atypical Squamous Cells of Undetermined Significance (ASC-US)

Repeat Cytology in 4-6 mo

HPV DNA Testing for High-Risk HPV Types

Colposcopy

Cytology Normal?

Yes

No (ASC-US or Worse)

HPV DNA Test Result Negative?

Yes

No

Colposcopy Normal?

Yes

No (CIN or cancer)

Prior HPV DNA Test. Result Negative or Unknown

Prior HPV DNA Test. Result Positive

Repeat Testing Normal?

Yes

No (ASC-US or worse Cytology or HPV DNA Positive)

Cytology Normal?

Yes

No (ASC-US or worse)

Colposcopy

Colposcopy

Colposcopy

Treatment as Indicated