(Legend)

Generic Name

• Oxazepam
  T½ = 5–15 h
  Protein binding = 97%
  Schedule IV
  Pregnancy category D

Trade Name

• Serax
• Novoxapam
• Oxpam

Dose Range/Adult Daily Dose

• Range: 30–120 mg/d
  Anxiety: 10–30 mg po 3–4 × daily
  Sedative/alcohol withdrawal: 15–30 mg po 3–4 × daily

Use/Common Side Effects (CSE)

• Use: Anxiety, alcohol withdrawal
  CSE: Dizziness, drowsiness, hangover, impaired memory, blurred vision, constipation, nausea

Geriatric & Dose Considerations

• ↓dose: Start 5 mg po 1–2 × daily, may increase as needed; caution w hepatic, severe COPD disease; ↑ risk for falls

Classification

• Antianxiety/sedative/hypnotic [benzo]

Assessment Cautions

• Contraindicated: CNS depression, coma, narrow-angle glaucoma, pregnancy, lactation
  Caution: Hepatic dysfunction; monitor CBCs, LFTs, avoid alcohol