(Legend)

Generic Name

• Propranolol
  T½ = 3.4–6 h
  Protein binding = 93%
  Pregnancy category C

Trade Name

• Inderal
• Apo-propranolol

Dose Range/Adult Daily Dose

• Tremors: 80–120 mg/d po (up to 320 mg/d)
  Akathisia: 30–120 mg/d po

Use/Common Side Effects (CSE)

• Use: Essential tremor, anxiety, akathisia
  CSE: Fatigue, weakness, impotence, ARRHYTHMIAS, BRADYCARDIA, CHF, PULMONARY EDEMA

Geriatric & Dose Considerations

• ↓dose (elderly have increased sensitivity to beta blockers); renal, hepatic, pulmonary disease, diabetes

Classification

• Antianginal/beta blocker

Assessment Cautions

• Contraindicated: Heart block, CHF, bradycardia. Monitor BP, pulse, & for orthostatic hypotension. Abrupt withdrawal: life-threatening arrhythmias.