(Legend)

Generic Name

• Selegiline Patch [MAOI]
  First transdermal patch delivering medication systemically over 24 h period.
  Protein binding = 90% over a 2–500 ng/mL concentration range.
  Pregnancy category C

Trade Name

• Emsam

Dose Range/Adult Daily Dose

• Range: 6 mg/24 h to 12 mg/24 h
  Recommended starting and target dose: 6 mg/24 h

Use/Common Side Effects (CSE)

• Use: Major depressive disorder
  CSE: Mild skin reaction/redness at patch site. D/C if redness continues for several hours after patch removal; hypotension, HYPERTENSION

Geriatric & Dose Considerations

• Patients 50 yr and older at higher risk for rash

Classification

• Antidepressant

Assessment Cautions

• With doses above 6 mg/24 h, must follow MAOI diet (foods high in tyramine). Hypertensive crisis is an emergency.
  Contraindicated: Amphetamines, pseudoephedrine, etc; other selegiline products (Eldepryl). Monitor BP, also for headache, nausea, stiff neck, palpitations. Close monitoring of children for suicidality. Read full prescribing information.