FDA WARNINGS (2007): The US Food and Drug Administration wants all makers of antidepressants to include warnings about increased risk for suicidality in young adults ages 18–24 during initial treatment. The FDA also wants all manufacturers of sedatives-hypnotics to warn about possible severe allergic reactions as well as complex sleep-related behaviors, such as sleep-driving. If angioedema develops, seek treatment and do not use drug again. Use of higher doses increases chance of next-day impairment of driving/alertness. Sources: Vallerand Davis’s Drug Guide 17th ed. 2020; prescribing information (package inserts); FDA Drug Updates.