WLI is indicated when there is no CR seen on CT at wk 6 after 3-drug chemo (per current protocol); it is not based on # of mets, size, or detectability on CT or CXR. The dose for WLI is 12 Gy (>1 yo) or 10.5 Gy (<1 yo) in 1.5 Gy/fx. If there is persistent Dz after WLI, consider a 7.5 Gy boost.