Adj Tx options after a pancreaticoduodenectomy:

1. Adj gemcitabine (CONKO-001)

2. Adj gemcitabine alone → 5-FU/RT→ gemcitabine alone (RTOG 9704)

3. Adj 5-FU/RT (GITSG 91-73); consider maintenance gemcitabine afterward

4. Adj 5-FU → 5-FU/RT → 5-FU (RTOG 9704)

5. Observation alone