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LN irradiation is controversial in the neoadj or definitive setting. In this setting, some institutions trend toward using smaller fields that treat gross tumor plus a small margin (McGinnCJ et al., JCO 2001), while others have continued to treat LN in the definitive setting (Ben-JosefE et al., IJROBP 2004). Recent Alliance (A021501) & NRG (RTOG 1201) cooperative group clinical trial designs have not involved elective LN RTin the neoadj or definitive setting, respectively.

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