section name header

Pronunciation

soo-doe-e-FED-rin audio

Indications

REMS

Action

Therapeutic Effects:

Pharmacokinetics

Absorption: Well absorbed after oral administration.

Distribution: Appears to enter the CSF; probably crosses the placenta and enters breast milk.

Metabolism/Excretion: Partially metabolized by the liver. 55–75% excreted unchanged by the kidneys (depends on urine pH).

Half-life: Children: 3.1 hr; Adults: 9–16 hr (depends on urine pH).

Contraind./Precautions

Contraindicated in:

Use Cautiously in:

Adv. Reactions/Side Effects

Neuro: SEIZURES, anxiety, nervousness, dizziness, drowsiness, excitability, fear, hallucinations, headache, insomnia, restlessness, weakness.

Resp: respiratory difficulty.

CV: CARDIOVASCULAR COLLAPSE, palpitations, hypertension, tachycardia.

GI: anorexia, dry mouth.

GU: dysuria.

Misc: diaphoresis.

Interactions

Drug-Drug:

Drug-Food:

Route/Dosage

see Calculator

Implementation

US Brand Names

Silfedrine Children's, Sudafed 12 Hour, Sudafed 24 Hour, Sudafed Children's, SudoGest, SudoGest 12 Hour

Classifications

Therapeutic Classification: allergy, cold and cough remedies, nasal drying agents/decongestants

Pharmacologic Classification: adrenergics

Availability

(Generic available)

Time/Action Profile

(decongestant effects)

ROUTEONSETPEAKDURATION
PO15–30 minunknown4–6 hr
PO-ER60 minunknown12 hr

Assessment

Pot. Nursing Diagnoses

Patient/Family Teaching

Evaluation/Desired Outcomes

Code

NDC Code*