Absorption: Well absorbed after oral administration.
Distribution: Appears to enter the CSF; probably crosses the placenta and enters breast milk.
Metabolism/Excretion: Partially metabolized by the liver. 5575% excreted unchanged by the kidneys (depends on urine pH).
Half-life: Children: 3.1 hr; Adults: 916 hr (depends on urine pH).
Contraindicated in:
Use Cautiously in:
Neuro: SEIZURES, anxiety, nervousness, dizziness, drowsiness, excitability, fear, hallucinations, headache, insomnia, restlessness, weakness.
Resp: respiratory difficulty.
CV: CARDIOVASCULAR COLLAPSE, palpitations, hypertension, tachycardia.
GI: anorexia, dry mouth.
GU: dysuria.
Misc: diaphoresis.
Drug-Drug:
Drug-Food:
Silfedrine Children's, Sudafed 12 Hour, Sudafed 24 Hour, Sudafed Children's, SudoGest, SudoGest 12 Hour
Therapeutic Classification: allergy, cold and cough remedies, nasal drying agents/decongestants
Pharmacologic Classification: adrenergics
(Generic available)
NDC Code*