klor-ZOX-a-zohn

• Adjunct to rest and physical therapy in the treatment of muscle spasm associated with acute painful musculoskeletal conditions.

• Skeletal muscle relaxation, probably due to CNS depression.

• Skeletal muscle relaxation with decreased discomfort.

Absorption: Readily absorbed after oral administration.

Distribution: Unknown.

Metabolism/Excretion: Mostly metabolized by the liver; <1% excreted unchanged in urine.

Half-life: 1.1 hr.

Contraindicated in:

• Hypersensitivity
• Porphyria.

Use Cautiously in:

• Underlying cardiovascular disease
• Impaired renal or hepatic function
• OB: Lactation: Pedi: Safety not established
• Geri: Appears on Beers list. Poorly tolerated due to anticholinergic effects.

CNS: dizziness, drowsiness.

GI: GI BLEEDING, constipation, diarrhea, heartburn, nausea, vomiting.

Derm: allergic dermatitis.

Hemat: AGRANULOCYTOSIS, anemia.

Misc: ALLERGIC REACTIONS INCLUDING ANGIOEDEMA.

Drug-Drug:

• ↑risk of CNS depression with other CNS depressants, including alcohol, antihistamines, antidepressants, sedative/hypnotics, or opioid analgesics.

Drug-Natural Products:

• Concomitant use of kava-kava, valerian, skullcap, chamomile, or hops can ↑ CNS depression.

• PO (Adults): 250–750 mg 3–4 times daily.
• PO (Children): 20 mg/kg or 600 mg/m²/day in 3–4 divided doses.

• PO: May be administered with meals to minimize gastric irritation. Tablets may be crushed and mixed with food or liquid for ease of administration.

Parafon Forte DSC

Therapeutic Classification: skeletal muscle relaxants (centrally acting)

(Generic available)

• Tablets: 375 mg; 500 mg; 750 mg;

(skeletal muscle effects)

• Assess patient for pain, muscle stiffness, and range of motion before and periodically during therapy.
• Geri: Assess geriatric patients for anticholinergic effects (sedation and weakness).

• Acute pain (Indications).
• Impaired physical mobility (Indications).
• Risk for injury (Side Effects).

• Instruct patient to take medication as directed; do not take more than the prescribed amount. Missed doses should be taken within 1 hr of time ordered; otherwise, omit and return to normal dose schedule. Do not double doses.
• Medication may cause drowsiness and dizziness. Caution patient to avoid driving or other activities requiring alertness until response to drug is known.
• Advise patient to avoid concurrent use of alcohol or other CNS depressants with this medication.
• If constipation becomes a problem, advise patient that increasing fluid intake and bulk in diet and stool softeners may alleviate this condition.

• Relief of muscular spasm in acute skeletal muscle conditions.

NDC Code^*

• 0591- Actavis Pharma, Inc.
  • 0591-2520- Chlorzoxazone
    • 0591-2520-01- 100 TABLET in 1 BOTTLE, PLASTIC (0591-2520-01)

• 0591- Actavis Pharma, Inc.
  • 0591-2520- Chlorzoxazone
    • 0591-2520-05- 500 TABLET in 1 BOTTLE, PLASTIC (0591-2520-05)

• 13811- Trigen Laboratories, LLC
  • 13811-717- chlorzoxazone
    • 13811-717-10- 100 TABLET in 1 BOTTLE, PLASTIC (13811-717-10)

• 13811- Trigen Laboratories, LLC
  • 13811-718- chlorzoxazone
    • 13811-718-10- 100 TABLET in 1 BOTTLE, PLASTIC (13811-718-10)

• 33261- Aidarex Pharmaceuticals LLC
  • 33261-021- Chlorzoxazone
    • 33261-021-30- 30 TABLET in 1 BOTTLE, PLASTIC (33261-021-30)

• 33261- Aidarex Pharmaceuticals LLC
  • 33261-021- Chlorzoxazone
    • 33261-021-60- 60 TABLET in 1 BOTTLE, PLASTIC (33261-021-60)

• 33261- Aidarex Pharmaceuticals LLC
  • 33261-021- Chlorzoxazone
    • 33261-021-90- 90 TABLET in 1 BOTTLE, PLASTIC (33261-021-90)

• 45865- Medsource Pharmaceuticals
  • 45865-434- Chlorzoxazone
    • 45865-434-20- 20 TABLET in 1 BOTTLE, PLASTIC (45865-434-20)

• 45865- Medsource Pharmaceuticals
  • 45865-434- Chlorzoxazone
    • 45865-434-30- 30 TABLET in 1 BOTTLE, PLASTIC (45865-434-30)

• 46672- Mikart Inc.
  • 46672-117- chlorzoxazone
    • 46672-117-10- 100 TABLET in 1 BOTTLE (46672-117-10)

• 46672- Mikart Inc.
  • 46672-117- chlorzoxazone
    • 46672-117-50- 500 TABLET in 1 BOTTLE (46672-117-50)

• 46672- Mikart Inc.
  • 46672-118- chlorzoxazone
    • 46672-118-10- 100 TABLET in 1 BOTTLE (46672-118-10)

• 46672- Mikart Inc.
  • 46672-118- chlorzoxazone
    • 46672-118-50- 500 TABLET in 1 BOTTLE (46672-118-50)

• 46672- Mikart, LLC
  • 46672-860- chlorzoxazone
    • 46672-860-05- 500 TABLET in 1 BOTTLE, PLASTIC (46672-860-05)

• 46672- Mikart, LLC
  • 46672-860- chlorzoxazone
    • 46672-860-10- 100 TABLET in 1 BOTTLE, PLASTIC (46672-860-10)

• 46672- Mikart, LLC
  • 46672-860- chlorzoxazone
    • 46672-860-46- 60 TABLET in 1 BOTTLE, PLASTIC (46672-860-46)

• 49999- Lake Erie Medical DBA Quality Care Products LLC
  • 49999-044- Chlorzoxazone
    • 49999-044-30- 30 TABLET in 1 BOTTLE, PLASTIC (49999-044-30)

• 49999- Lake Erie Medical DBA Quality Care Products LLC
  • 49999-044- Chlorzoxazone
    • 49999-044-60- 60 TABLET in 1 BOTTLE, PLASTIC (49999-044-60)

• 49999- Lake Erie Medical DBA Quality Care Products LLC
  • 49999-044- Chlorzoxazone
    • 49999-044-90- 90 TABLET in 1 BOTTLE, PLASTIC (49999-044-90)

• 50090- A-S Medication Solutions
  • 50090-0315- Chlorzoxazone
    • 50090-0315-0- 30 TABLET in 1 BOTTLE (50090-0315-0)

• 50090- A-S Medication Solutions
  • 50090-0315- Chlorzoxazone
    • 50090-0315-1- 20 TABLET in 1 BOTTLE (50090-0315-1)

• 50090- A-S Medication Solutions
  • 50090-0315- Chlorzoxazone
    • 50090-0315-3- 60 TABLET in 1 BOTTLE (50090-0315-3)

• 50090- A-S Medication Solutions
  • 50090-0315- Chlorzoxazone
    • 50090-0315-4- 40 TABLET in 1 BOTTLE (50090-0315-4)

• 50090- A-S Medication Solutions
  • 50090-0316- Chlorzoxazone
    • 50090-0316-0- 7 TABLET in 1 BOTTLE (50090-0316-0)

• 53002- RPK Pharmaceuticals, Inc.
  • 53002-5760- Chlorzoxazone
    • 53002-5760-1- 10 TABLET in 1 BOTTLE (53002-5760-1)

• 53002- RPK Pharmaceuticals, Inc.
  • 53002-5760- Chlorzoxazone
    • 53002-5760-2- 20 TABLET in 1 BOTTLE (53002-5760-2)

• 53002- RPK Pharmaceuticals, Inc.
  • 53002-5760- Chlorzoxazone
    • 53002-5760-3- 30 TABLET in 1 BOTTLE (53002-5760-3)

• 53002- RPK Pharmaceuticals, Inc.
  • 53002-5760- Chlorzoxazone
    • 53002-5760-5- 15 TABLET in 1 BOTTLE (53002-5760-5)

• 55289- PD-Rx Pharmaceuticals, Inc.
  • 55289-633- Chlorzoxazone
    • 55289-633-10- 10 TABLET in 1 BOTTLE, PLASTIC (55289-633-10)

• 55289- PD-Rx Pharmaceuticals, Inc.
  • 55289-633- Chlorzoxazone
    • 55289-633-20- 20 TABLET in 1 BOTTLE, PLASTIC (55289-633-20)

• 55289- PD-Rx Pharmaceuticals, Inc.
  • 55289-633- Chlorzoxazone
    • 55289-633-24- 24 TABLET in 1 BOTTLE, PLASTIC (55289-633-24)

• 55289- PD-Rx Pharmaceuticals, Inc.
  • 55289-633- Chlorzoxazone
    • 55289-633-28- 28 TABLET in 1 BOTTLE, PLASTIC (55289-633-28)

• 55289- PD-Rx Pharmaceuticals, Inc.
  • 55289-633- Chlorzoxazone
    • 55289-633-30- 30 TABLET in 1 BOTTLE, PLASTIC (55289-633-30)

• 55289- PD-Rx Pharmaceuticals, Inc.
  • 55289-633- Chlorzoxazone
    • 55289-633-40- 40 TABLET in 1 BOTTLE, PLASTIC (55289-633-40)

• 55700- Lake Erie Medical DBA Quality Care Products LLC
  • 55700-517- Lorzone
    • 55700-517-30- 30 TABLET in 1 BOTTLE, PLASTIC (55700-517-30)

• 63187- Proficient Rx LP
  • 63187-317- Chlorzoxazone
    • 63187-317-20- 20 TABLET in 1 BOTTLE, PLASTIC (63187-317-20)

• 63187- Proficient Rx LP
  • 63187-317- Chlorzoxazone
    • 63187-317-30- 30 TABLET in 1 BOTTLE, PLASTIC (63187-317-30)

• 63187- Proficient Rx LP
  • 63187-317- Chlorzoxazone
    • 63187-317-60- 60 TABLET in 1 BOTTLE, PLASTIC (63187-317-60)

• 63187- Proficient Rx LP
  • 63187-317- Chlorzoxazone
    • 63187-317-90- 90 TABLET in 1 BOTTLE, PLASTIC (63187-317-90)

• 66267- NuCare Pharmaceuticals, Inc.
  • 66267-055- Chlorzoxazone
    • 66267-055-40- 40 TABLET in 1 BOTTLE, PLASTIC (66267-055-40)

• 68025- Vertical Pharmaceuticals, Inc.
  • 68025-046- Lorzone
    • 68025-046-10- 100 TABLET in 1 BOTTLE, PLASTIC (68025-046-10)

• 68025- Vertical Pharmaceuticals, Inc.
  • 68025-047- Lorzone
    • 68025-047-02- 2 POUCH in 1 BOX, UNIT-DOSE (68025-047-02) > 1 TABLET in 1 POUCH (68025-047-01)

• 68025- Vertical Pharmaceuticals, Inc.
  • 68025-047- Lorzone
    • 68025-047-10- 100 TABLET in 1 BOTTLE, PLASTIC (68025-047-10)

• 69499- Solubiomix
  • 69499-330- chlorzoxazone
    • 69499-330-60- 60 TABLET in 1 BOTTLE, PLASTIC (69499-330-60)

• 70518- REMEDYREPACK INC.
  • 70518-0496- Chlorzoxazone
    • 70518-0496-0- 40 TABLET in 1 BOTTLE, PLASTIC (70518-0496-0)

• 70518- REMEDYREPACK INC.
  • 70518-0496- Chlorzoxazone
    • 70518-0496-1- 30 TABLET in 1 BOTTLE, PLASTIC (70518-0496-1)

• 70518- REMEDYREPACK INC.
  • 70518-2053- Chlorzoxazone
    • 70518-2053-0- 20 TABLET in 1 BOTTLE, PLASTIC (70518-2053-0)

• 70518- REMEDYREPACK INC.
  • 70518-2053- Chlorzoxazone
    • 70518-2053-1- 40 TABLET in 1 BOTTLE, PLASTIC (70518-2053-1)

• 70954- Novitium Pharma LLC
  • 70954-085- Chlorzoxazone
    • 70954-085-10- 100 TABLET in 1 BOTTLE (70954-085-10)

• 70954- Novitium Pharma LLC
  • 70954-085- Chlorzoxazone
    • 70954-085-20- 500 TABLET in 1 BOTTLE (70954-085-20)