section name header

Pronunciation

a-NI-du-la-fun-gin audio

Classifications

Therapeutic Classification: antifungals

Pharmacologic Classification: echinocandins

Indications

REMS

Action

Therapeutic Effects:

Spectrum:

Pharmacokinetics

Absorption: IV administration results in complete bioavailability.

Distribution: Widely distributed to tissues.

Metabolism/Excretion: Undergoes chemical degradation without hepatic metabolism; <1% excreted in urine.

Half-life: 40–50 hr.

Time/Action Profile

(plasma concentrations)

ROUTEONSETPEAKDURATION
IVrapidend of infusion24 hr

Contraind./Precautions

Contraindicated in:

Use Cautiously in:

Adv. Reactions/Side Effects

CV: hypotension.

Derm: flushing, rash, urticaria.

F and E: hypokalemia.

GI: ↑ liver enzymes, diarrhea.

Resp: bronchospasm, dyspnea.

Misc: ANAPHYLAXIS, infusion reactions.

Interactions

Drug-Drug:

Route/Dosage

Candidemia and Intra-abdominal Abscess or Peritonitis Caused by Candida

Esophageal Candidiasis

Availability

Assessment

Lab Test Considerations:

Implementation

IV Administration:

Patient/Family Teaching

Evaluation/Desired Outcomes

US Brand Names

Eraxis

Code

NDC Code*