SOE-dee-um bye-KAR-boe-nate 
Unlabeled Use:
Absorption: Following oral administration, excess bicarbonate is absorbed and results in metabolic alkalosis and alkaline urine. IV administration results in complete bioavailability.
Distribution: Widely distributed into extracellular fluid.
Metabolism/Excretion: Sodium and bicarbonate are excreted by the kidneys.
Half-life: Unknown.
(PO = antacid effect; IV = alkalinization)
| ROUTE | ONSET | PEAK | DURATION |
|---|---|---|---|
| PO | immediate | 30 min | 1–3 hr |
| IV | immediate | rapid | unknown |
Contraindicated in:
Use Cautiously in:
CV: edema.
F and E: metabolic alkalosis, hypernatremia, hypocalcemia, hypokalemia.
GI: PO: flatulence, gastric distention.
Local: irritation at IV site.
Neuro: cerebral hemorrhage (with rapid injection in infants), tetany.
Drug-Drug:
Alkalinization of Urine
Antacid
Systemic Alkalinization/Cardiac Arrest
(Generic available)
IV Administration:
NDC Code*