section name header

Pronunciation ⬇

BIZ-muth sub-sa-LIS-i-late audio

Classifications ⬆ ⬇

Therapeutic Classification: antidiarrheals, antiulcer agents

Pharmacologic Classification: adsorbents

Indications ⬆ ⬇

REMS

Unlabeled Use:

Action ⬆ ⬇

Therapeutic Effects:

Pharmacokinetics ⬆ ⬇

Absorption: Bismuth is not absorbed; salicylate split from parent compound is >90% absorbed from the small intestine. Salicylate is highly bound to albumin.

Distribution: Salicylate crosses the placenta and enters breast milk.

Metabolism/Excretion: Bismuth is excreted unchanged in the feces. Salicylate undergoes extensive hepatic metabolism.

Half-life: Salicylate — 2–3 hr for low doses; 15–30 hr with larger doses.

Time/Action Profile ⬆ ⬇

(relief of diarrhea and other GI symptoms)

ROUTEONSETPEAKDURATION
POwithin 24 hrunknownunknown

Contraind./Precautions ⬆ ⬇

Contraindicated in:

Use Cautiously in:

Adv. Reactions/Side Effects ⬆ ⬇

GI: constipation, gray-black stools, impaction (infants, debilitated patients).

Interactions ⬆ ⬇

Drug-Drug:

Route/Dosage ⬆ ⬇

Availability ⬆ ⬇

(Generic available)

Assessment ⬆ ⬇

Lab Test Considerations:

Implementation ⬆ ⬇

Patient/Family Teaching ⬆ ⬇

Evaluation/Desired Outcomes ⬆ ⬇

US Brand Names ⬆ ⬇

Bismatrol, Kaopectate, Kao-Tin, Kapectolin, Peptic Relief, Pepto-Bismol

Pot. Nursing Diagnoses ⬆ ⬇

Code ⬆

NDC Code*