Absorption: Well absorbed after oral administration but rapidly undergoes extensive metabolism.
Distribution: Small amounts appear in breast milk.
Metabolism/Excretion: Extensively metabolized by the liver and other tissues.
Half-life: Oral 2.75 hr; Inhalation: 3.8 hr.
Contraindicated in:
Use Cautiously in:
CV: chest pain, palpitations, angina, arrhythmias, hypertension.
Endo: hyperglycemia.
F and E: hypokalemia.
GI: nausea, vomiting.
Neuro: nervousness, restlessness, tremor, headache, hyperactivity (children), insomnia.
Drug-Drug:
Drug-Natural Products:
12 yr): 24 mg 34 times daily (not to exceed 32 mg/day).
4 yr): Via metered-dose inhaler or dry powder inhaler: 2 inhalations every 46 hr (some patients may respond to 1 inhalation) or 2 inhalations 15 min before exercise; NIH Guidelines for acute asthma exacerbation: Children: 48 puffs every 20 min for 3 doses then every 14 hr; Adults: 48 puffs every 20 min for up to 4 hr then every 14 hr as needed.(Generic available)
Accuneb, Proair Digihaler, Proair HFA, Proair Respiclick, Proventil HFA, Ventolin HFA, VoSpire ER
NDC Code*