Therapeutic Classification: antihypertensives
Pharmacologic Classification: angiotensin II receptor antagonists
REMS
Absorption: 1035% absorbed following oral administration.
Distribution: Crosses the placenta.
Protein Binding: 95%.
Half-Life: 6 hr.
(antihypertensive effect)
ROUTE | ONSET | PEAK | DURATION |
---|---|---|---|
PO | within 2 hr* | 4 wks‡ | 24 hr‡ |
*After single dose.
‡Chronic dosing.
Contraindicated in:
Use Cautiously in:
CV: edema, hypotension
EENT: pharyngitis, rhinitis, sinusitis
F and E: hyperkalemia
GI: abdominal pain, diarrhea, nausea
GU: impaired renal function
MS: arthralgia, back pain
Neuro: dizziness, fatigue, headache
Misc: ANGIOEDEMA
Drug-drug:
Hypertension
Heart Failure
Post-Myocardial Infarction
Lab Test Considerations:
NDC Code