section name header

Pronunciation ⬇

be-THAN-e-kole

Classifications ⬆ ⬇

Therapeutic Classification: urinary tract stimulant

Pharmacologic Classification: cholinergics

Indications ⬆ ⬇

REMS

Action ⬆ ⬇

  • Stimulates cholinergic receptors. Effects include:
    • Contraction of the urinary bladder,
    • Decreased bladder capacity,
    • Increased frequency of ureteral peristaltic waves,
    • Increased tone and peristalsis in the GI tract,
    • Increased pressure in the lower esophageal sphincter,
    • Increased gastric secretions.
Therapeutic effects:
  • Bladder emptying.

Pharmacokinetics ⬆ ⬇

Absorption: Poorly absorbed after oral administration.

Distribution: Does not cross the blood-brain barrier.

Metabolism/Excretion: Unknown.

Half-Life: Unknown.

Time/Action Profile ⬆ ⬇

(response on bladder muscle)

ROUTEONSETPEAKDURATION
PO30–90 min1 hr6 hr



Contraind./Precautions ⬆ ⬇

Contraindicated in:

Use Cautiously in:

Adv. Reactions/Side Effects ⬆ ⬇

CV: bradycardia, HEART BLOCK, hypotension, SYNCOPE/CARDIAC ARREST

EENT: lacrimation, miosis

GI: vomiting, abdominal discomfort, diarrhea, nausea, salivation

GU: urgency

Neuro: headache, malaise

Resp: bronchospasm

Misc: sweating, flushing, hypothermia

Interactions ⬆ ⬇

Drug-drug:

Drug-Natural Products:

Route/Dosage ⬆ ⬇

Availability ⬆ ⬇

(Generic available)

Assessment ⬆ ⬇

Lab Test Considerations:

Toxicity and Overdose:

Implementation ⬆ ⬇

Patient/Family Teaching ⬆ ⬇

Evaluation/Desired Outcomes ⬆ ⬇

US Brand Names ⬆ ⬇

Duvoid, Urecholine

Code ⬆

NDC Code