Absorption: Systemic absorption follows epidural administration, but amount absorbed depends on dose.
Distribution: If systemic absorption occurs, this agent is widely distributed and crosses the placenta.
Half-Life: 4.2 hr (after epidural use).
Contraindicated in:
Use Cautiously in:
CV: CARDIOVASCULAR COLLAPSE, arrhythmias, bradycardia, chest pain, hypertension, hypotension, tachycardia
Derm: pruritus
F and E: hypokalemia, metabolic acidosis
Hemat: METHEMOGLOBINEMIA, anemia
MS: chondrolysis
Neuro: circumoral tingling/numbness, paresthesia, SEIZURES, anxiety, dizziness, headache, rigors
Resp: dyspnea
Misc: HYPERSENSITIVITY REACTIONS (INCLUDING ANGIOEDEMA AND ANAPHYLAXIS), fever
Drug-drug:
Surgical Anesthesia
Labor Pain
Postoperative Pain
Major nerve block
(Adults ): 3550 mL of 0.5% solution or 1040 mL of 0.75% solution.Field block
(Adults ): 140 mL of 0.5% solution.Infiltration (minor nerve block)
(Adults ): 1100 mL of 0.2% solution or 140 mL of 0.5% solution.NDC Code