BEERS REMS
Absorption: Variable absorption from tablets. Well absorbed following IM administration.
Distribution: Widely distributed; high CNS concentrations.
Protein Binding: ≥90%.
Half-Life: 30 hr.
(antipsychotic activity, antiemetic activity, sedation)
ROUTE | ONSET | PEAK | DURATION |
---|---|---|---|
PO | 3060 min | unknown | 46 hr |
IM | unknown | unknown | 48 hr |
IV | rapid | unknown | unknown |
Contraindicated in:
Use Cautiously in:
CV: hypotension (↑ with IM, IV), tachycardia
Derm: photosensitivity, pigment changes, rash
EENT: blurred vision, dry eyes, lens opacities
Endo: amenorrhea, galactorrhea
GI: constipation, dry mouth, anorexia, hepatitis, ileus, priapism
Hemat: AGRANULOCYTOSIS, leukopenia
Neuro: sedation, extrapyramidal reactions, NEUROLEPTIC MALIGNANT SYNDROME, tardive dyskinesia
Misc: allergic reactions
Drug-drug:
Drug-Natural Products:
Lab Test Considerations:
IV Administration:
NDC Code