section name header

Pronunciation ⬇

me-JESS-trole

Classifications ⬆ ⬇

Therapeutic Classification: antineoplastics, hormones

Pharmacologic Classification: progestins

Indications ⬆ ⬇

BEERS REMS

Action ⬆ ⬇

Therapeutic Effects:

Pharmacokinetics ⬆ ⬇

Absorption: Well absorbed from the GI tract.

Distribution: Unknown.

Protein Binding: ge.gif90%.

Metabolism/Excretion: Completely metabolized by the liver.

Half-life: 38 hr (range 13–104 hr).

Time/Action Profile ⬆ ⬇

(antineoplastic activity)

ROUTEONSETPEAKDURATION
POwk–mos2 mounknown

Contraind./Precautions ⬆ ⬇

Contraindicated in:

Use Cautiously in:

Adv. Reactions/Side Effects ⬆ ⬇

CV: edema, THROMBOEMBOLISM.

Derm: alopecia.

Endo: asymptomatic adrenal suppression (chronic therapy).

GI: GI irritation.

GU: vaginal bleeding.

MS: carpal tunnel syndrome.

Interactions ⬆ ⬇

Drug-Drug:

Route/Dosage ⬆ ⬇

Availability ⬆ ⬇

(Generic available)

Assessment ⬆ ⬇

Lab Test Considerations:

Implementation ⬆ ⬇

Patient/Family Teaching ⬆ ⬇

Evaluation/Desired Outcomes ⬆ ⬇

US Brand Names ⬆ ⬇

Megace

Code ⬆

NDC Code*