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Pronunciation ⬇

fex-oh-FEN-a-deen

Classifications ⬆ ⬇

Therapeutic Classification: allergy, cold and cough remedies

Pharmacologic Classification: antihistamines

Indications ⬆ ⬇

REMS

Action ⬆ ⬇

  • Antagonizes the effects of histamine at peripheral histamine–1 (H1) receptors, including pruritus and urticaria.
  • Also has a drying effect on the nasal mucosa.
Therapeutic effects:
  • Decreased sneezing, rhinorrhea, itchy eyes, nose, and throat associated with seasonal allergies.
  • Decreased urticaria.

Pharmacokinetics ⬆ ⬇

Absorption: Rapidly absorbed after oral administration.

Distribution: Unknown.

Metabolism/Excretion: 80% excreted in urine, 11% excreted in feces.

Half-Life: 14.4 hr (↑ in renal impairment).

Time/Action Profile ⬆ ⬇

(antihistaminic effect)

ROUTEONSETPEAKDURATION
POwithin 1 hr2–3 hr12–24 hr



Contraind./Precautions ⬆ ⬇

Contraindicated in:

Use Cautiously in:

Adv. Reactions/Side Effects ⬆ ⬇

GI: dyspepsia

GU: dysmenorrhea

Neuro: drowsiness, fatigue

Interactions ⬆ ⬇

Drug-drug:

Route/Dosage ⬆ ⬇

Renal Impairment

Availability ⬆ ⬇

(Generic available)

Assessment ⬆ ⬇

Lab Test Considerations:

Implementation ⬆ ⬇

Patient/Family Teaching ⬆ ⬇

Evaluation/Desired Outcomes ⬆ ⬇

US Brand Names ⬆ ⬇

Allegra, Allegra Allergy, Children's Allegra Allergy, Children's Allegra Hives, Mucinex Allergy

Pill Image

fexofenadine_135-990.jpg

Code ⬆

NDC Code