Therapeutic Classification: antiretrovirals
Pharmacologic Classification: nucleoside reverse transcriptase inhibitors
Absorption: Rapidly and extensively (83%) absorbed.
Distribution: Distributes into extravascular space and readily distributes into erythrocytes.
Metabolism/Excretion: Mostly metabolized by the liver; 1.2% excreted unchanged in urine.
Half-life: 1.5 hr.
Contraindicated in:
Use Cautiously in:
Derm: rash.
F and E: LACTIC ACIDOSIS.
GI: diarrhea, nausea, vomiting, anorexia, HEPATOMEGALY (WITH STEATOSIS).
Neuro: headache, insomnia.
Misc: HYPERSENSITIVITY REACTIONS, immune reconstitution syndrome.
Drug-Drug:
(Generic available)
NDC Code*