AT-ro-peen
Therapeutic Classification: antiarrhythmics
Pharmacologic Classification: anticholinergics, antimuscarinics
BEERS REMS
Absorption: Well absorbed following SUBQ administration. IV administration results in complete bioavailability.
Distribution: Readily crosses the blood-brain barrier. Crosses the placenta and enters breast milk.
Half-Life: Children <2 yr: 4–10 hr; Children >2 yr: 1.5–3.5 hr; Adults: 4–5 hr.
Contraindicated in:
Use Cautiously in:
CV: tachycardia, arrhythmias, palpitations
Derm: ↓sweating, flushing
EENT: blurred vision, cycloplegia, dry eyes, mydriasis, photophobia
GI: dry mouth, constipation, impaired GI motility
GU: urinary hesitancy, impotency, retention
Neuro: drowsiness, confusion
Resp: pulmonary edema, tachypnea
Drug-drug:
Preanesthesia (To Decrease Salivation/Secretions)
Bradycardia
Endotracheal
(Children ): use the IV dose and dilute before administration.Reversal of Adverse Muscarinic Effects of Anticholinesterases
Bronchospasm
Inhaln
(Adults ): 0.025–0.05 mg/kg/dose every 4–6 hr as needed; maximum 2.5 mg/dose.Inhaln
(Children ): 0.03–0.05 mg/kg/dose 3–4 times/day; maximum 2.5 mg/dose.Rate: Inject directly into the endotracheal tube followed by several positive pressure ventilations.
IV Administration:
NDC Code