Absorption: Well absorbed after oral or IM administration. IV administration results in complete bioavailability.
Distribution: Extensively distributed to tissues.
Half-Life: Unknown.
(antimotion sickness, antiemetic activity)
ROUTE | ONSET | PEAK | DURATION |
---|---|---|---|
PO | 1560 min | 12 hr | 36 hr |
IM | 2030 min | 12 hr | 36 hr |
IV | rapid | unknown | 36 hr |
Contraindicated in:
Use Cautiously in:
CV: hypotension, palpitations
Derm: photosensitivity
EENT: blurred vision, tinnitus
GI: anorexia, constipation, diarrhea, dry mouth
GU: dysuria, urinary frequency
Local: pain at IM site
Neuro: drowsiness, dizziness, headache, paradoxical excitation (children)
Drug-drug:
Lab Test Considerations:
IV Administration:
NDC Code