dox-AY-zoe-sin
Therapeutic Classification: antihypertensives
Pharmacologic Classification: peripherally acting antiadrenergics
BEERS REMS
Absorption: Well absorbed following oral administration.
Distribution: Unknown.
Protein Binding: 98–99%.
Half-Life: 22 hr.
| ROUTE | ONSET | PEAK | DURATION |
|---|---|---|---|
| PO‡ | 1–2 hr | 2–6 hr | 24 hr |
| PO-XL‡ | 5 wk | unknown | unknown |
‡Antihypertensive effect.
‡Improved urinary flow and BPH symptoms.
Contraindicated in:
Use Cautiously in:
CV: first-dose orthostatic hypotension, arrhythmias, chest pain, edema, palpitations
Derm: flushing, rash, urticaria
EENT: blurred vision, conjunctivitis, epistaxis, intraoperative floppy iris syndrome
GI: abdominal discomfort, constipation, diarrhea, dry mouth, flatulence, nausea, vomiting
GU: ↓libido, priapism, sexual dysfunction
MS: arthralgia, myalgia
Neuro: dizziness, headache, depression, drowsiness, fatigue, nervousness, weakness.
Resp: dyspnea
Drug-drug:
Hypertension
NDC Code