section name header

Pronunciation ⬇

me-TAX-a-lone

Classifications ⬆ ⬇

Therapeutic Classification: skeletal muscle relaxants (centrally acting)

Indications ⬆ ⬇

BEERS REMS

Action ⬆ ⬇

  • Skeletal muscle relaxation, probably as a result of CNS depression.
Therapeutic effects:
  • Skeletal muscle relaxation.

Pharmacokinetics ⬆ ⬇

Absorption: Well absorbed following oral administration.

Distribution: Unknown.

Metabolism/Excretion: Mostly metabolized by the liver; metabolites excreted in urine.

Half-Life: 2–3 hr.

Time/Action Profile ⬆ ⬇

ROUTEONSETPEAKDURATION
PO1 hr2 hr4–6 hr

Contraind./Precautions ⬆ ⬇

Contraindicated in:

Use Cautiously in:

Adv. Reactions/Side Effects ⬆ ⬇

GI: nausea, anorexia, dry mouth, GI upset, vomiting

GU: urinary retention

Neuro: dizziness, drowsiness, confusion, headache, irritability, nervousness

Misc: SEROTONIN SYNDROME

Interactions ⬆ ⬇

Drug-drug:

Drug-Natural Products:

Route/Dosage ⬆ ⬇

Availability ⬆ ⬇

(Generic available)

Assessment ⬆ ⬇

Lab Test Considerations:

Implementation ⬆ ⬇

Patient/Family Teaching ⬆ ⬇

Evaluation/Desired Outcomes ⬆ ⬇

US Brand Names ⬆ ⬇

Skelaxin

Code ⬆

NDC Code