REMS
Absorption: 90%.
Distribution: Only small quantities are found in the systemic circulation; sites of action include the liver, bile, and gut lumen.
Protein Binding: 70%.
Half-Life: 100 hr.
Contraindicated in:
Use Cautiously in:
Derm: hair thinning, pruritus, rash
GI: abdominal/biliary pain, constipation, diarrhea, flatulence, jaundice, ↑liver enzymes, nausea, stomatitis, vomiting
Neuro: arthralgias, myalgia
Resp: cough, rhinitis
Drug-drug:
Lab Test Considerations:
NDC Code