vitamin b complex with vitamin c

Therapeutic Classification: vitamins

Pharmacologic Classification: water soluble vitamins

Indications ⬆ ⬇

REMS

Treatment and prevention of vitamin deficiencies.

Action ⬆ ⬇

Contain most or all of the B-complex vitamins (B₁, B₂, B₃, B₅, B₆, B₁₂) and vitamin C, a diverse group of compounds necessary for normal growth and development that act as coenzymes or catalysts in numerous metabolic processes.

Therapeutic effects:

Replacement of vitamins in patients who are deficient or at risk for deficiency.

Pharmacokinetics ⬆ ⬇

Absorption: Well absorbed after oral administration. Some absorptive processes require cofactors (B₁₂).

Distribution: Widely distributed; cross the placenta and enter breast milk.

Metabolism/Excretion: Used in various biologic processes. Excess amounts are excreted unchanged by the kidneys.

Half-Life: Unknown.

Time/Action Profile ⬆ ⬇

ROUTE	ONSET	PEAK	DURATION
PO	unknown	unknown	unknown

Contraind./Precautions ⬆ ⬇

Contraindicated in:

Hypersensitivity to ingredients in preparations (benzyl alcohol, parabens, bisulfites, tartrazine).

Use Cautiously in:

Undiagnosed anemias.

Adv. Reactions/Side Effects ⬆ ⬇

In recommended doses, adverse reactions are extremely rare

GU: bright-yellow urine

Misc: allergic reactions to preservatives, ANAPHYLAXIS (VITAMIN B1-THIAMINE)₁-thiamine)

Interactions ⬆ ⬇

Drug-drug:

Large amounts of vitamin B₆ may interfere with the beneficial effect of levodopa.

Route/Dosage ⬆ ⬇

PO IV (Adults and Children ): Amount sufficient to meet RDA for age group.

Availability ⬆ ⬇

Tablets, capsules, sublingual liquid: contain vitamins B₁ (6–50 mg); B₂ (5–50 mg); B₃ (20–150 mg); B₅ (10–50 mg); B₆ (4–50 mg); vitamin B₁₂ (0–1000 mcg); and vitamin C (50–600 mg) per tablet, capsule, or mL^OTC
In combination with: folic acid, biotin, chromium, soy protein, brewers yeast, potassium, manganese, and zinc in multivitamin/mineral productsRx, OTC.
Injection: contains vitamin B₁ (50 mg), B₂ (5 mg), B₃ (125 mg), B₅ (6 mg), B₁₂ (1000 mcg), and vitamin C (50 mg/mL)

Assessment ⬆ ⬇

Assess patient for signs of vitamin deficiency before and periodically during therapy. Assess nutritional status through 24-hr diet recall. Determine frequency of consumption of vitamin-rich foods. Therapy is limited to periods of high physiologic stress when patient is not able to ingest adequate vitamins orally.
Monitor patient for anaphylaxis (wheezing, urticaria, edema); contains thiamine.

Implementation ⬆ ⬇

IV Administration:

Usually administered as part of a large-volume parenteral admixture.

Patient/Family Teaching ⬆ ⬇

Encourage patient to comply with diet recommendations of health care professional. Explain that the best source of vitamins is a well-balanced diet with foods from the four basic food groups.

Evaluation/Desired Outcomes ⬆ ⬇

Prevention of or decrease in the symptoms of vitamin deficiencies.

US Brand Names ⬆

Albee-T, Albee with C, Arcobee with C, B-Complex/Vitamin C, Beminal, Econo B & C, Enviro-Stress, Farbee with Vitamin C, Gen-bee with C, High Potency N-Vites, Nion B Plus C, Probec-T, Sublingual B Total Liquid, Surbex T, Surbu-Gen-T, Surplex-T, Therapeutic B Complex with C, ThexForte, T-Vites, Vicon-C, Viogen-C, Vita-Bee with C, Key Plex, Neurodep, Vicam

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Classifications ⬇