li-NEZ-o-lid
REMS
Spectrum:
Absorption: Rapidly and extensively (100%) absorbed following oral administration. IV administration results in complete bioavailability.
Distribution: Readily distributes to well-perfused tissues.
Half-Life: 6.4 hr.
Contraindicated in:
Use Cautiously in:
Derm: toxic epidermal necrolysis
EENT: teeth discoloration, tongue discoloration
Endo: hypoglycemia, syndrome of inappropriate diuretic hormone (SIADH) secretion
F and E: hyponatremia, lactic acidosis
GI: ↑liver enzymes, CLOSTRIDIOIDES DIFFICILE-ASSOCIATED DIARRHEA (CDAD), diarrhea, nausea, vomiting
Hemat: anemia, leukopenia, thrombocytopenia
MS: RHABDOMYOLYSIS
Neuro: dysgeusia, optic neuropathy, peripheral neuropathy
Misc: SEROTONIN SYNDROME
Drug-drug:
Drug-Food:
Vancomycin-Resistant Enterococcus faecium Infections
Pneumonia or Complicated Skin/Skin Structure Infections
Uncomplicated Skin/Skin Structure Infections
Lab Test Considerations:
IV Administration:
NDC Code