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Pronunciation ⬇

DOK-yoo-sate

Classifications ⬆ ⬇

Therapeutic Classification: laxatives

Pharmacologic Classification: stool softeners

Indications ⬆ ⬇

REMS

Action ⬆ ⬇

  • Promotes incorporation of water into stool, resulting in softer fecal mass.
  • May also promote electrolyte and water secretion into the colon.
Therapeutic effects:
  • Softening and passage of stool.

Pharmacokinetics ⬆ ⬇

Absorption: Small amounts may be absorbed from the small intestine after oral administration. Absorption from the rectum is not known.

Distribution: Unknown.

Metabolism/Excretion: Amounts absorbed after oral administration are eliminated in bile.

Half-Life: Unknown.

Time/Action Profile ⬆ ⬇

(softening of stool)

ROUTEONSETPEAKDURATION
PO12–72 hrunknownunknown
Rectal2–15 minunknownunknown

Contraind./Precautions ⬆ ⬇

Contraindicated in:

Use Cautiously in:

Adv. Reactions/Side Effects ⬆ ⬇

Derm: rash

EENT: throat irritation

GI: diarrhea, mild cramps

Interactions ⬆ ⬇

Drug-drug:

Route/Dosage ⬆ ⬇

Docusate Calcium

Docusate Sodium

Availability ⬆ ⬇

(Generic available)

Docusate Calcium

Docusate Sodium

(Generic available)

Assessment ⬆ ⬇

Implementation ⬆ ⬇

Patient/Family Teaching ⬆ ⬇

Evaluation/Desired Outcomes ⬆ ⬇

US Brand Names ⬆ ⬇

docusate sodium: Colace, DOK, Dulcolax Stool Softener, Enemeez Mini, Silace

Canadian Brand Names ⬆ ⬇

docusate sodium: Selax, Soflax

Code ⬆

NDC Code