(Adults and Children ≥9 yr): Apply once daily in the evening.
Availability⬆⬇
Topical cream: 0.005%
Assessment⬆⬇
Assess skin lesions before and periodically during therapy.
Implementation⬆⬇
Topical Cleanse the area to be treated; pat dry. Apply a thin layer of cream to affected areas once daily, in the evening, on clean and dry skin. One pump actuation should be enough to cover the face (forehead, cheeks, nose, chin). Two actuations of pump should be enough to cover the upper trunk (reachable upper back, shoulders chest). One additional pump actuation may be used for middle and lower back if acne is present. Avoid contact with the eyes, lips, paranasal creases, and mucous membranes. Cream is for topical use only; avoid oral, ophthalmic, and intravaginal use.
Use moisturizer as frequently as needed from start of treatment. Avoid contact with the eyes, lips, paranasal creases, mucous membranes.
Patient/Family Teaching⬆⬇
Instruct patient on application technique. Advise patient to read Patient Information before starting therapy and with each Rx refill in case of changes.
Inform patient that erythema, scaling, dryness, and stinging/burning may occur, with greatest severity within the first 4 weeks of therapy. Severity usually decreases with continued use of trifarotene. Instruct patient to use a moisturizer, reduce the frequency of application, or suspend use temporarily. If severe reactions persist therapy may be discontinued.
Advise patient to avoid application to cuts, abrasions, or eczematous or sunburned skin and to avoid use of “waxing” as a depilatory method in the area treated.
Caution patient to minimize unprotected exposure to ultraviolet rays (including sunlight and sunlamps) during therapy. Warn patients who normally experience high levels of sun exposure and those with inherent sensitivity to sun to exercise caution. Use sunscreen products and protective clothing over treated areas when exposure cannot be avoided.
Advise patient to avoid concomitant use of other potentially irritating topical products (medicated or not).
Instruct patient to notify health care professional of all Rx or OTC medications, vitamins, or herbal products being taken and to consult with health care professional before taking other medications.
Rep: Advise females of reproductive potential to notify health care professional if pregnancy is planned or suspected or if breastfeeding. If breastfeeding, use cream on the smallest area of skin and for the shortest duration possible to minimize potential exposure to the breastfed infant via breast milk. Advise breastfeeding women not to apply cream directly to nipple and areola to avoid direct infant exposure.
Evaluation/Desired Outcomes⬆⬇
Decreased severity of acne vulgaris.
US Brand Names⬆⬇
Aklief
Code⬆
NDC Code
0299- Galderma Laboratories, L.P.
0299-5935- AKLIEF
0299-5935-02- 1 TUBE in 1 BLISTER PACK (0299-5935-02) / 2 g in 1 TUBE
0299- Galderma Laboratories, L.P.
0299-5935- AKLIEF
0299-5935-45- 1 BOTTLE, PUMP in 1 CARTON (0299-5935-45) / 45 g in 1 BOTTLE, PUMP
17337- Olon S.p.A.
17337-0432-
17337-0432-0- 1 BAG in 1 DRUM (17337-0432-0) / 1 BOTTLE, GLASS in 1 BAG / .5 kg in 1 BOTTLE, GLASS
