Therapeutic Classification: antidiabetics
Pharmacologic Classification: glucagon like peptide 1 glp 1 receptor agonists, glucose dependent insulinotropic polypeptide gip receptor agonists
REMS
Absorption: 80% absorbed following subcutaneous administration.
Distribution: Minimally distributed to tissues.
Protein Binding: 99%.
Half-Life: 5 days.
Contraindicated in:
Use Cautiously in:
CV: ↑HR, hypotension
Derm: hair loss
EENT: retinopathy complications
Endo: hypoglycemia, MEDULLARY THYROID CARCINOMA
GI: ↓appetite, constipation, diarrhea, nausea, vomiting, ↑amylase, ↑lipase, abdominal distension, abdominal pain, cholecystitis, cholelithiasis, dyspepsia, flatulence, gastroesophageal reflux disease, PANCREATITIS
GU: acute kidney injury
Local: injection site reactions
Neuro: dizziness, dysesthesia, dysgeusia, fatigue, SUICIDAL THOUGHTS/BEHAVIOR
Resp: aspiration
Misc: HYPERSENSITIVITY REACTIONS (INCLUDING ANAPHYLAXIS AND ANGIOEDEMA)
Drug-drug:
Type 2 Diabetes
Chronic Weight Management
Obstructive Sleep Apnea
Lab Test Considerations:
NDC Code