astragalus

section name header

Pronunciation ⬇

a-STRAG-uh-luh-s

Classifications ⬆ ⬇

Therapeutic Classification: allergy, cold and cough remedies

Indications ⬆ ⬇

Complementary/Alternative Medicine: This monograph describes a natural or herbal product that is not subject to FDA guidelines for medicines. Patients and clinicians are advised to read package labels carefully to ensure safe and efficacious use.

REMS

Common cold.
Allergic rhinitis.

Action ⬆ ⬇

Astragalus has antioxidant effects. It inhibits free radical production, increases superoxide dismutase, and decreases lipid peroxidation. Astragalus potentiates effects of interferon, increases antibody levels of IgA and IgG in nasal secretions, and increases interleukin-2 (IL-2) levels.

Therapeutic effects:

Improved immune response.

Pharmacokinetics ⬆ ⬇

Absorption: Unknown.

Distribution: Unknown.

Metabolism/Excretion: Unknown.

Half-Life: Unknown.

Time/Action Profile ⬆ ⬇

ROUTE	ONSET	PEAK	DURATION
unknown	unknown	unknown	unknown

Contraind./Precautions ⬆ ⬇

Contraindicated in:

No known contraindications.

Use Cautiously in:

Pregnancy and lactation;
May exacerbate autoimmune diseases.

Adv. Reactions/Side Effects ⬆ ⬇

GI: nausea

Misc: immunosuppression (with doses >28 grams/day)

Interactions ⬆ ⬇

Natural-Drug Products:

May reduce the effects ofimmunosuppressants.
May reduce excretion and increase levels of lithium.

Natural-Natural Products:

None.

Route/Dosage ⬆ ⬇

PO (Adults ): Allergic rhinitis:160 mg of astragalus root extract twice daily. Common cold prevention:4–7 g per day.

Availability ⬆ ⬇

Capsules: 470 mg

Assessment ⬆ ⬇

Assess signs and symptoms of cold and rhinitis (congestion, runny nose, aches).

Implementation ⬆ ⬇

PO: May be taken as capsules. Also available as a tincture or fluid extract.

Patient/Family Teaching ⬆ ⬇

Discuss purpose of astragalus with patient.
Advise patient to notify health care professional of all Rx or OTC medications, vitamins, or herbal products being taken and to consult with health care professional before taking other medications.
Advise female patient to notify health care professional if pregnancy is planned or suspected or if breastfeeding.

Evaluation/Desired Outcomes ⬆ ⬇

Improvement in symptoms of cold or allergic rhinitis.

US Brand Names ⬆

Astragali Membranaceus, Membranous Milk Vetch