budesonide (inhalation)

byoo-DES-oh-nide

Therapeutic Classification: corticosteroids

Pharmacologic Classification: corticosteroids

REMS

Maintenance treatment of asthma.

Potent, locally acting anti-inflammatory and immune modifier.

Therapeutic effects:

Decreases frequency/severity of asthma attacks.
Improves asthma symptoms.

Absorption: Flexhaler: 39%; Respules: 6%. Action is primarily local following inhalation.

Distribution: Well distributed to tissues.

Protein Binding: 85–90%.

Metabolism/Excretion: Primarily metabolized by the liver via the CYP3A4 isoenzyme following absorption from lungs; 60% excreted in urine, 40% in feces.

Half-Life: Adults: 2–3.6 hr; Children 10–14 yr: 1.5 hr; Children 4–6 yr: 2.3 hr (after nebulization).

(improvement in symptoms)

ROUTE	ONSET	PEAK	DURATION
Inhaln	within 24 hr	1–4 wk‡	unknown
Nebulization	with 2–8 days	4–6 wk	unknown

‡Improvement in pulmonary function; decreased airway responsiveness may take longer.

Contraindicated in:

Hypersensitivity;
Acute attack of asthma/status asthmaticus.

Use Cautiously in:

Active untreated infection;
Diabetes;
Glaucoma;
Underlying immunosuppression (from disease or concurrent therapy);
Systemic corticosteroid therapy (should not be abruptly discontinued when inhaled therapy is started; additional corticosteroids needed during stress or trauma);
OB: Use during pregnancy only if potential maternal benefit justifies potential fetal risk;
Lactation: Use while breastfeeding only if potential maternal benefit justifies potential risk to infant;
Pedi: Higher than recommended doses in children can lead to suppression of hypothalamic-pituitary-adrenal (HPA) function and suppression of linear growth.

Derm: rash

EENT: otitis media, dysphonia, epistaxis, oropharyngeal fungal infections, pharyngitis, rhinitis, sinusitis

Endo: ↓growth (children), adrenal suppression (high dose, long-term therapy only)

GI: abdominal pain, diarrhea, dyspepsia, gastroenteritis, nausea, vomiting

Metab: weight gain

MS: back pain

Neuro: headache

Resp: bronchospasm, cough

Misc: ANAPHYLAXIS, flu-like syndrome

Drug-drug:

Strong CYP3A4 inhibitors, including ritonavir, atazanavir, clarithromycin, , itraconazole, ketoconazole, nefazodone, and nelfinavir, may ↑ levels and risk of toxicity.

Flexhaler
Inhaln (Adults ): 180–360 mcg twice daily (not to exceed 720 mcg twice daily).
Inhaln (Children ≥6 yr): 180–360 mcg twice daily (not to exceed 360 mcg twice daily).
Respules
Inhaln (Children 1–8 yr): Previously on bronchodilators alone:0.5 mg once daily or 0.25 mg twice daily (not to exceed 0.5 mg/day); Previously on other inhaled corticosteroids: 0.5 mg once daily or 0.25 mg twice daily (not to exceed 1 mg/day); Previously on oral corticosteroids: 1 mg once daily or 0.5 mg twice daily (not to exceed 1 mg/day).

(Generic available)

Inhalation powder (Flexhaler): 90 mcg/metered inhalation (delivers 60 metered inhalations); 100 mcg/metered inhalation (delivers 200 metered inhalations); 180 mcg/metered inhalation (delivers 120 metered inhalations); 200 mcg/metered inhalation (delivers 200 metered inhalations); 400 mcg/metered inhalation (delivers 200 metered inhalations)
Inhalation suspension (Respules): 0.25 mg/2 mL in single dose ampules (5 ampules/envelope); 0.5 mg/2 mL in single dose ampules (5 ampules/envelope); 1 mg/2 mL in single dose ampules (5 ampules/envelope)
In combination with:
albuterol (Airsupra); formoterol (Breyna, Symbicort); formoterol and glycopyrrolate (Breztri Aerosphere); see Combination Drugs.

Monitor respiratory status and lung sounds. Assess pulmonary function tests (FEV1) periodically for several months following a transition from systemic to inhaled corticosteroids.
Assess patients changing from systemic to inhaled corticosteroids for signs/symptoms of adrenal insufficiency (anorexia, nausea, weakness, fatigue, hypotension, hypoglycemia) during initial therapy and periods of stress. If adrenal insufficiency occurs, notify health care provider immediately; condition may be life-threatening.
Monitor for withdrawal symptoms (fatigue, weakness, nausea, vomiting, hypotension, joint or muscular pain, lassitude, depression) during weaning from oral corticosteroids.
Monitor for glaucoma and/or cataracts when used long-term; assess for changes in vision or ↑ intraocular pressure.
Pedi: Monitor growth rates every 3 to 6 mo in children receiving chronic therapy; use lowest possible dose.

Lab Test Considerations:

Periodic adrenal function tests may be ordered to assess degree of hypothalamic-pituitary-adrenal (HPA) axis suppression in chronic therapy. Patients using ↑ doses are at highest risk for HPA suppression.
- May ↑ serum and urine glucose concentrations if significant absorption occurs.

After the desired clinical effect has been obtained, attempts should be made to ↓ dose to lowest required to control symptoms. Gradually ↓ dose every 2–4 wk as long as desired effect is maintained. If asthma symptoms return, dose may briefly return to starting dose.
Inhaln: Prime inhaler prior to initial use only. Allow ≥1 min between inhalations of Flexhaler. Do not shake inhaler or use with spacer. After inhalation, rinse mouth with water and then spit out the water.

Explain the purpose and side effects of budesonide. Advise patient to take as directed. Instruct patient or caregiver in correct technique for inhalation. Take missed doses as soon as remembered unless almost time for next dose. Advise patient not to discontinue medication without consulting health care professional; gradual ↓ is required. Instruct patient to read the Patient Information before using and with each Rx refill, in case of changes.
Advise patients using inhaled corticosteroids and bronchodilator to use bronchodilator 1st and to allow 5 min to elapse before administering the corticosteroid, unless otherwise directed by health care professional.
Advise patient that inhaled corticosteroids should not be used to treat an acute asthma attack but should be continued even if other inhalation agents are used.
Patients using inhaled corticosteroids to control asthma may require systemic corticosteroids for acute attacks. Teach patient to use regular peak flow monitoring to determine respiratory status.
Advise patient to rinse mouth with water after treatment to ↓ risk of developing local candidiasis.
Caution patient to avoid smoking, known allergens, and other respiratory irritants.
Advise patient to notify health care professional if sore throat or mouth or signs/symptoms of anaphylaxis (rash, severe itching, swelling of the face, mouth, and tongue, trouble breathing or swallowing, chest pain, anxiety or feeling of doom) occur.
Instruct patient whose systemic corticosteroids have been recently ↓ or withdrawn to carry a warning card indicating the need for supplemental systemic corticosteroids in the event of stress or severe asthma attack unresponsive to bronchodilators.
Advise patient to notify health care professional of all Rx or OTC medications, vitamins, or herbal products being taken and to consult with health care professional before taking other medications.
Pulmicort Flexhaler: Advise patient to follow instructions supplied. Before first-time use, prime unit by turning cover and lifting off; hold upright with mouthpiece up and twist brown grip fully to right, then fully to left until it clicks. To administer dose, hold upright, twist brown grip fully to right, then fully to left, until it clicks. Turn head away from inhaler and exhale (do not blow into inhaler). Do not shake inhaler. Place mouthpiece between lips and inhale deeply and forcefully. Remove inhaler from mouth and exhale (do not exhale into mouthpiece). Repeat procedure if 2nd dose required. Replace cover.
Pulmicort Respules: Administer with a jet nebulizer connected to adequate air flow, equipped with a mouthpiece or face mask. Adjust face mask to avoid exposing eyes to nebulized medication. Wash face after use of face mask. Ultrasonic nebulizers are not adequate for administration and not recommended.
- Store respules upright, away from heat and protected from light. Do not refrigerate or freeze. Respules are stable for 2 wk at room temperature after opening aluminum foil envelope. Open respules must be used promptly. Unused respules should be returned to aluminum foil envelope.
Rep: Advise women of reproductive potential to notify health care professional if pregnancy is planned or suspected or if breastfeeding. Monitor infants for signs of hypoadrenalism, including poor feeding, irritability, weakness, and vomiting, and manage accordingly.

Improvement in asthma symptoms.
Decreased frequency/severity of asthma attacks.

Pulmicort Respules, Pulmicort Flexhaler

Pulmicort Nebuamp, Pulmicort Turbuhaler

NDC Code

0093- Teva Pharmaceuticals USA, Inc.
- 0093-6815- Budesonide
  - 0093-6815-55- 30 POUCH in 1 CARTON (0093-6815-55) / 1 VIAL, SINGLE-DOSE in 1 POUCH / 2 mL in 1 VIAL, SINGLE-DOSE

0093- Teva Pharmaceuticals USA, Inc.
- 0093-6815- Budesonide
  - 0093-6815-73- 6 POUCH in 1 CARTON (0093-6815-73) / 5 VIAL, SINGLE-DOSE in 1 POUCH (0093-6815-45) / 2 mL in 1 VIAL, SINGLE-DOSE (0093-6815-19)

0093- Teva Pharmaceuticals USA, Inc.
- 0093-6815- Budesonide
  - 0093-6815-76- 2 POUCH in 1 CARTON (0093-6815-76) / 5 VIAL, SINGLE-DOSE in 1 POUCH / 2 mL in 1 VIAL, SINGLE-DOSE

0093- Teva Pharmaceuticals USA, Inc.
- 0093-6816- Budesonide
  - 0093-6816-55- 30 POUCH in 1 CARTON (0093-6816-55) / 1 VIAL, SINGLE-DOSE in 1 POUCH / 2 mL in 1 VIAL, SINGLE-DOSE

0093- Teva Pharmaceuticals USA, Inc.
- 0093-6816- Budesonide
  - 0093-6816-73- 6 POUCH in 1 CARTON (0093-6816-73) / 5 VIAL, SINGLE-DOSE in 1 POUCH (0093-6816-45) / 2 mL in 1 VIAL, SINGLE-DOSE (0093-6816-19)

0093- Teva Pharmaceuticals USA, Inc.
- 0093-6816- Budesonide
  - 0093-6816-76- 2 POUCH in 1 CARTON (0093-6816-76) / 5 VIAL, SINGLE-DOSE in 1 POUCH / 2 mL in 1 VIAL, SINGLE-DOSE

0093- Teva Pharmaceuticals USA, Inc.
- 0093-6817- Budesonide
  - 0093-6817-73- 6 POUCH in 1 CARTON (0093-6817-73) / 5 AMPULE in 1 POUCH (0093-6817-45) / 2 mL in 1 AMPULE (0093-6817-19)

0115- Amneal Pharmaceuticals of New York LLC
- 0115-1687- Budesonide Inhalation
  - 0115-1687-74- 6 POUCH in 1 CARTON (0115-1687-74) / 5 VIAL in 1 POUCH (0115-1687-76) / 2 mL in 1 VIAL

0115- Amneal Pharmaceuticals of New York LLC
- 0115-1689- Budesonide Inhalation
  - 0115-1689-74- 6 POUCH in 1 CARTON (0115-1689-74) / 5 VIAL in 1 POUCH (0115-1689-76) / 2 mL in 1 VIAL

0186- AstraZeneca Pharmaceuticals LP
- 0186-0916- PULMICORT FLEXHALER
  - 0186-0916-12- 1 INHALER in 1 CARTON (0186-0916-12) / 120 AEROSOL, POWDER in 1 INHALER

0186- AstraZeneca Pharmaceuticals LP
- 0186-0917- PULMICORT FLEXHALER
  - 0186-0917-06- 1 INHALER in 1 CARTON (0186-0917-06) / 60 AEROSOL, POWDER in 1 INHALER

0186- AstraZeneca Pharmaceuticals LP
- 0186-1988- PULMICORT RESPULES
  - 0186-1988-04- 6 POUCH in 1 CARTON (0186-1988-04) / 5 AMPULE in 1 POUCH / 2 mL in 1 AMPULE

0186- AstraZeneca Pharmaceuticals LP
- 0186-1989- PULMICORT RESPULES
  - 0186-1989-04- 6 POUCH in 1 CARTON (0186-1989-04) / 5 AMPULE in 1 POUCH / 2 mL in 1 AMPULE

0186- AstraZeneca Pharmaceuticals LP
- 0186-1990- PULMICORT RESPULES
  - 0186-1990-04- 6 POUCH in 1 CARTON (0186-1990-04) / 5 AMPULE in 1 POUCH / 2 mL in 1 AMPULE

0363- Walgreens
- 0363-0048- Budesonide
  - 0363-0048-01- 1 BOTTLE, SPRAY in 1 BOTTLE, SPRAY (0363-0048-01) / 120 SPRAY, METERED in 1 BOTTLE, SPRAY

0378- Mylan Pharmaceuticals Inc.
- 0378-4500- Budesonide
  - 0378-4500-93- 30 TABLET, FILM COATED, EXTENDED RELEASE in 1 BOTTLE, PLASTIC (0378-4500-93)

0487- Nephron Pharmaceuticals Corporation
- 0487-9601- Budesonide
  - 0487-9601-01- 6 POUCH in 1 CARTON (0487-9601-01) / 5 AMPULE in 1 POUCH / 2 mL in 1 AMPULE

0487- Nephron Pharmaceuticals Corporation
- 0487-9601- Budesonide
  - 0487-9601-30- 30 POUCH in 1 CARTON (0487-9601-30) / 1 AMPULE in 1 POUCH / 2 mL in 1 AMPULE

0487- Nephron Pharmaceuticals Corporation
- 0487-9701- Budesonide
  - 0487-9701-01- 6 POUCH in 1 CARTON (0487-9701-01) / 5 AMPULE in 1 POUCH / 2 mL in 1 AMPULE

0487- Nephron Pharmaceuticals Corporation
- 0487-9701- Budesonide
  - 0487-9701-30- 30 POUCH in 1 CARTON (0487-9701-30) / 1 AMPULE in 1 POUCH / 2 mL in 1 AMPULE

0536- Rugby Laboratories
- 0536-1112- Budesonide
  - 0536-1112-48- 1 BOTTLE, SPRAY in 1 CARTON (0536-1112-48) / 120 SPRAY, METERED in 1 BOTTLE, SPRAY

0574- Padagis US LLC
- 0574-9855- budesonide
  - 0574-9855-10- 1 BOTTLE in 1 CARTON (0574-9855-10) / 100 CAPSULE in 1 BOTTLE

0591- Actavis Pharma, Inc.
- 0591-2510- Budesonide
  - 0591-2510-30- 30 TABLET, FILM COATED, EXTENDED RELEASE in 1 BOTTLE (0591-2510-30)

0781- Sandoz Inc
- 0781-7515- Budesonide
  - 0781-7515-87- 6 POUCH in 1 CARTON (0781-7515-87) / 5 AMPULE in 1 POUCH (0781-7515-14) / 2 mL in 1 AMPULE (0781-7515-72)

0781- Sandoz Inc
- 0781-7516- Budesonide
  - 0781-7516-87- 6 POUCH in 1 CARTON (0781-7516-87) / 5 AMPULE in 1 POUCH (0781-7516-14) / 2 mL in 1 AMPULE (0781-7516-72)

0781- Sandoz Inc
- 0781-7517- Budesonide
  - 0781-7517-87- 6 POUCH in 1 CARTON (0781-7517-87) / 5 AMPULE in 1 POUCH (0781-7517-14) / 2 mL in 1 AMPULE (0781-7517-72)

0904- Major Pharmaceuticals
- 0904-7313- budesonide
  - 0904-7313-10- 20 BLISTER PACK in 1 CARTON (0904-7313-10) / 1 CAPSULE, COATED PELLETS in 1 BLISTER PACK

11822- Rite Aid Corporation
- 11822-1700- Budesonide
  - 11822-1700-1- 1 BOTTLE, SPRAY in 1 CARTON (11822-1700-1) / 120 SPRAY, METERED in 1 BOTTLE, SPRAY

15308- Aarti Pharmalabs Limited
- 15308-0100-
  - 15308-0100-0- 25 kg in 1 DRUM (15308-0100-0)

16714- Northstar Rx LLC.
- 16714-829- budesonide
  - 16714-829-01- 100 CAPSULE, COATED PELLETS in 1 BOTTLE (16714-829-01)

38779- Medisca Inc.
- 38779-3097-
  - 38779-3097-0- .5 g in 1 JAR (38779-3097-0)

38779- Medisca Inc.
- 38779-3097-
  - 38779-3097-3- 5 g in 1 JAR (38779-3097-3)

38779- Medisca Inc.
- 38779-3097-
  38779-3097-4- 25 g in 1 JAR (38779-3097-4)

38779- Medisca Inc.
- 38779-3097-
  38779-3097-5- 100 g in 1 JAR (38779-3097-5)

38779- Medisca Inc.
- 38779-3097-
  38779-3097-6- 1 g in 1 JAR (38779-3097-6)

45802- Padagis Israel Pharmaceuticals Ltd
- 45802-627- BUDESONIDE
  45802-627-86- 2 CANISTER in 1 CARTON (45802-627-86) / 1 AEROSOL, FOAM in 1 CANISTER (45802-627-01)

46439- Farmabios S.p.A.
- 46439-8719-
  - 46439-8719-1- 2500 g in 1 DRUM (46439-8719-1)

46439- Farmabios S.p.A.
- 46439-8719-
  46439-8719-2- 1500 g in 1 DRUM (46439-8719-2)

46439- Farmabios S.p.A.
- 46439-8737-
  46439-8737-1- 1000 g in 1 CAN (46439-8737-1)

46439- Farmabios S.p.A.
- 46439-8780-
  46439-8780-1- 1000 g in 1 CARTON (46439-8780-1)

46439- Farmabios S.p.A.
- 46439-8780-
  46439-8780-2- 1500 g in 1 DRUM (46439-8780-2)

47335- Sun Pharmaceutical Industries, Inc.
- 47335-631- Budesonide
  47335-631-49- 6 POUCH in 1 CARTON (47335-631-49) / 5 AMPULE in 1 POUCH (47335-631-48) / 2 mL in 1 AMPULE

47335- Sun Pharmaceutical Industries, Inc.
- 47335-632- Budesonide
  - 47335-632-49- 6 POUCH in 1 CARTON (47335-632-49) / 5 AMPULE in 1 POUCH (47335-632-48) / 2 mL in 1 AMPULE

47335- Sun Pharmaceutical Industries, Inc.
- 47335-633- Budesonide
  - 47335-633-49- 6 POUCH in 1 CARTON (47335-633-49) / 5 AMPULE in 1 POUCH (47335-633-48) / 2 mL in 1 AMPULE

49035- EQUATE (Wal-Mart Stores, Inc.) (see also WAL-MART INC)
- 49035-703- Budesonide
  - 49035-703-01- 1 BOTTLE, SPRAY in 1 BOTTLE, SPRAY (49035-703-01) / 120 SPRAY, METERED in 1 BOTTLE, SPRAY

49076- Coral Drugs Private Limited
- 49076-6111-
  - 49076-6111-1- 20 kg in 1 CARTON (49076-6111-1)

49076- Coral Drugs Private Limited
- 49076-6111-
  49076-6111-2- 50 kg in 1 DRUM (49076-6111-2)

49452- Spectrum Laboratory Products, Inc.
- 49452-1292-
  49452-1292-1- .0005 kg in 1 BOTTLE, GLASS (49452-1292-1)

49452- Spectrum Laboratory Products, Inc.
- 49452-1292-
  49452-1292-2- .001 kg in 1 BOTTLE, GLASS (49452-1292-2)

49452- Spectrum Laboratory Products, Inc.
- 49452-1292-
  49452-1292-3- .005 kg in 1 BOTTLE, GLASS (49452-1292-3)

49452- Spectrum Laboratory Products, Inc.
- 49452-1292-
  49452-1292-4- .025 kg in 1 CONTAINER (49452-1292-4)

49452- Spectrum Laboratory Products, Inc.
- 49452-1292-
  49452-1292-5- .1 kg in 1 CONTAINER (49452-1292-5)

49452- Spectrum Laboratory Products, Inc.
- 49452-1292-
  49452-1292-6- 1 kg in 1 CONTAINER (49452-1292-6)

49927- Minakem Dunkerque Production
- 49927-0004-
  49927-0004-0- 8 kg in 1 BOTTLE (49927-0004-0)

50090- A-S Medication Solutions
- 50090-1467- Budesonide
  50090-1467-0- 30 VIAL in 1 CARTON (50090-1467-0) / 2 mL in 1 VIAL

50090- A-S Medication Solutions
- 50090-2239- PULMICORT FLEXHALER
  - 50090-2239-0- 1 INHALER in 1 CARTON (50090-2239-0) / 120 AEROSOL, POWDER in 1 INHALER

50090- A-S Medication Solutions
- 50090-6586- Budesonide
  - 50090-6586-0- 6 POUCH in 1 CARTON (50090-6586-0) / 5 AMPULE in 1 POUCH / 2 mL in 1 AMPULE

50090- A-S Medication Solutions
- 50090-6590- Budesonide
  - 50090-6590-0- 6 POUCH in 1 CARTON (50090-6590-0) / 5 AMPULE in 1 POUCH / 2 mL in 1 AMPULE

50090- A-S Medication Solutions
- 50090-6796- PULMICORT FLEXHALER
  - 50090-6796-0- 1 INHALER in 1 CARTON (50090-6796-0) / 120 AEROSOL, POWDER in 1 INHALER

50090- A-S Medication Solutions
- 50090-7173- Budesonide
  - 50090-7173-0- 30 AMPULE in 1 CARTON (50090-7173-0) / 2 mL in 1 AMPULE

50546- Mayne Pharma International Pty Ltd
- 50546-580-
  - 50546-580-99- 1 BAG in 1 DRUM (50546-580-99) / 20000 CAPSULE, DELAYED RELEASE PELLETS in 1 BAG

51407- Golden State Medical Supply, Inc.
- 51407-128- BUDESONIDE (ENTERIC COATED)
  51407-128-01- 100 CAPSULE, DELAYED RELEASE PELLETS in 1 BOTTLE (51407-128-01)

51407- Golden State Medical Supply, Inc.
- 51407-591- budesonide
  - 51407-591-01- 100 CAPSULE in 1 BOTTLE (51407-591-01)

51407- Golden State Medical Supply, Inc.
- 51407-824- Budesonide
  - 51407-824-30- 30 TABLET, FILM COATED, EXTENDED RELEASE in 1 BOTTLE (51407-824-30)

51508- Hubei Gedian Humanwell Pharmaceutical Co., Ltd
- 51508-004-
  - 51508-004-01- 1 kg in 1 CAN (51508-004-01)

51508- Hubei Gedian Humanwell Pharmaceutical Co., Ltd
- 51508-004-
  51508-004-03- 2.5 kg in 1 CAN (51508-004-03)

51508- Hubei Gedian Humanwell Pharmaceutical Co., Ltd
- 51508-004-
  51508-004-10- 10 kg in 1 DRUM (51508-004-10)

51508- Hubei Gedian humanwell Pharmaceutical Co., Ltd
- 51508-208-
  51508-208-01- 1 kg in 1 CONTAINER, FLEXIBLE INTERMEDIATE BULK (51508-208-01)

51508- Hubei Gedian humanwell Pharmaceutical Co., Ltd
- 51508-208-
  51508-208-25- 25 kg in 1 CONTAINER, FLEXIBLE INTERMEDIATE BULK (51508-208-25)

51862- Mayne Pharma Inc.
- 51862-580- BUDESONIDE (ENTERIC COATED)
  51862-580-01- 100 CAPSULE, DELAYED RELEASE PELLETS in 1 BOTTLE (51862-580-01)

52128- Symbiotica Speciality Ingredients Sdn. Bhd.
- 52128-133-
  - 52128-133-01- 1 kg in 1 CONTAINER (52128-133-01)

52221- Amphastar Nanjing Pharmaceuticals, Inc.
- 52221-117-
  52221-117-00- 1 CAN in 1 CARTON (52221-117-00) / 1 BAG in 1 CAN / 2000 g in 1 BAG

53104- Cipla Ltd.
- 53104-7617-
  53104-7617-1- 25 kg in 1 DRUM (53104-7617-1)

53183- Sicor S.r.l.
- 53183-6310-
  53183-6310-1- 1 kg in 1 CARTON (53183-6310-1)

53746- Amneal Pharmaceuticals of New York LLC
- 53746-778- Budesonide
  53746-778-10- 100 CAPSULE, DELAYED RELEASE in 1 BOTTLE (53746-778-10)

55154- Cardinal Health 107, LLC
- 55154-4849- Budesonide
  - 55154-4849-5- 5 VIAL, SINGLE-DOSE in 1 BAG (55154-4849-5) / 2 mL in 1 VIAL, SINGLE-DOSE

59651- Aurobindo Pharma Limited
- 59651-585- BUDESONIDE
  - 59651-585-30- 6 POUCH in 1 CARTON (59651-585-30) / 5 AMPULE in 1 POUCH (59651-585-05) / 2 mL in 1 AMPULE

60505- Apotex Corp.
- 60505-6129- Budesonide
  - 60505-6129-2- 1 BOTTLE, SPRAY in 1 BOTTLE, SPRAY (60505-6129-2) / 120 SPRAY, METERED in 1 BOTTLE, SPRAY

60505- Apotex Corp.
- 60505-6129- Budesonide
  - 60505-6129-6- 2 BOTTLE, SPRAY in 1 CARTON (60505-6129-6) / 120 SPRAY, METERED in 1 BOTTLE, SPRAY

60505- Apotex Corp.
- 60505-6129- Budesonide
  - 60505-6129-7- 3 BOTTLE, SPRAY in 1 CARTON (60505-6129-7) / 120 SPRAY, METERED in 1 BOTTLE, SPRAY

60687- American Health Packaging
- 60687-596- Budesonide
  - 60687-596-32- 20 BLISTER PACK in 1 BOX, UNIT-DOSE (60687-596-32) / 1 CAPSULE, COATED PELLETS in 1 BLISTER PACK (60687-596-33)

60870- Aspen Oss B.V.
- 60870-0466-
  - 60870-0466-0- 1 BAG in 1 DRUM (60870-0466-0) / 20000 g in 1 BAG

61269- H2-Pharma LLC
- 61269-509- PULMICORT FLEXHALER
  61269-509-06- 1 INHALER in 1 CARTON (61269-509-06) / 60 AEROSOL, POWDER in 1 INHALER

61269- H2-Pharma LLC
- 61269-518- PULMICORT FLEXHALER
  - 61269-518-12- 1 INHALER in 1 CARTON (61269-518-12) / 120 AEROSOL, POWDER in 1 INHALER

62135- Chartwell RX, LLC
- 62135-822- Budesonide
  - 62135-822-84- 6 POUCH in 1 CARTON (62135-822-84) / 5 AMPULE in 1 POUCH / 2 mL in 1 AMPULE

62135- Chartwell RX, LLC
- 62135-823- Budesonide
  - 62135-823-84- 6 POUCH in 1 CARTON (62135-823-84) / 5 AMPULE in 1 POUCH / 2 mL in 1 AMPULE

63190- Industriale Chimica s.r.l.
- 63190-0060-
  - 63190-0060-3- 30 kg in 1 DRUM (63190-0060-3)

63190- Industriale Chimica s.r.l.
- 63190-0060-
  63190-0060-5- 5 kg in 1 DRUM (63190-0060-5)

63592- Sicor de Mexico S.A. de C.V
- 63592-0187-
  63592-0187-2- 1 kg in 1 CARTON (63592-0187-2)

63629- Bryant Ranch Prepack
- 63629-8294- Budesonide
  63629-8294-1- 30 CAPSULE, DELAYED RELEASE in 1 BOTTLE (63629-8294-1)

63629- Bryant Ranch Prepack
- 63629-9093- budesonide
  - 63629-9093-1- 30 TABLET, EXTENDED RELEASE in 1 BOTTLE (63629-9093-1)

64764- TAKEDA PHARMACEUTICALS AMERICA, INC.
- 64764-105- Eohilia
  - 64764-105-00- 10 POUCH in 1 CARTON (64764-105-00) / 10 mL in 1 POUCH (64764-105-01)

64764- TAKEDA PHARMACEUTICALS AMERICA, INC.
- 64764-105- Eohilia
  - 64764-105-60- 60 POUCH in 1 CARTON (64764-105-60) / 10 mL in 1 POUCH (64764-105-10)

64918- Sterling S.p.A.
- 64918-0204-
  - 64918-0204-0- 20 kg in 1 DRUM (64918-0204-0)

64918- Sterling S.p.A.
- 64918-0205-
  64918-0205-0- 20 kg in 1 DRUM (64918-0205-0)

64958- Henan Lihua Pharmaceutical Co Ltd
- 64958-0104-
  64958-0104-0- 1 kg in 1 CAN (64958-0104-0)

64980- Rising Pharma Holdings, Inc.
- 64980-638- Budesonide
  64980-638-03- 30 POUCH in 1 CARTON (64980-638-03) / 5 AMPULE in 1 POUCH / 2 mL in 1 AMPULE

64980- Rising Pharma Holdings, Inc.
- 64980-639- Budesonide
  - 64980-639-03- 30 POUCH in 1 CARTON (64980-639-03) / 5 AMPULE in 1 POUCH / 2 mL in 1 AMPULE

65089- Curia Spain, S.A.U.
- 65089-0005-
  - 65089-0005-1- 1 kg in 1 DRUM (65089-0005-1)

65089- Curia Spain, S.A.U.
- 65089-0024-
  65089-0024-1- 1 kg in 1 DRUM (65089-0024-1)

65162- Amneal Pharmaceuticals LLC
- 65162-778- Budesonide
  65162-778-10- 100 CAPSULE, DELAYED RELEASE in 1 BOTTLE (65162-778-10)

section name header

Pronunciation ⬇

Classifications ⬆ ⬇

Indications ⬆ ⬇

Action ⬆ ⬇

Pharmacokinetics ⬆ ⬇

Time/Action Profile ⬆ ⬇

Contraind./Precautions ⬆ ⬇

Adv. Reactions/Side Effects ⬆ ⬇

Interactions ⬆ ⬇

Route/Dosage ⬆ ⬇

Availability ⬆ ⬇

Assessment ⬆ ⬇

Implementation ⬆ ⬇

Patient/Family Teaching ⬆ ⬇

Evaluation/Desired Outcomes ⬆ ⬇

US Brand Names ⬆ ⬇

Canadian Brand Names ⬆ ⬇

Code ⬆