Two-Tiered Test for Lyme Disease
Two-Tiered Test for Lyme Disease - Flowchart Two-Tiered Test for Lyme Disease Two-Tiered Test for Lyme Disease
«Flowchart»

First Test

Enzyme Immunoasssay (EIA)

OR

Immunofluorescence Assay (IFA)

First Test

Enzyme Immunoasssay (EIA)

OR

Immunofluorescence Assay (IFA)

First Test

First Test

Enzyme Immunoasssay (EIA)

OR

OR

Immunofluorescence Assay (IFA)

End

End

End

Consider alternative diagnosis

OR

If patient with signs/symptoms consistent with Lyme disease for ≤30 days, consider obtaining a convalescent serum

Consider alternative diagnosis

OR

If patient with signs/symptoms consistent with Lyme disease for ≤30 days, consider obtaining a convalescent serum

Consider alternative diagnosis

OR

OR

If patient with signs/symptoms consistent with Lyme disease for ≤30 days, consider obtaining a convalescent serum

≤

Positive or Equivocal Result

Positive or Equivocal Result

Positive or Equivocal Result

Negative Result

Negative Result

Negative Result

Second Test

IgM and IgG Western Blot

Second Test

IgM and IgG Western Blot

Second Test

Second Test

IgM and IgG Western Blot

Signs or symptoms ≤30 days

Signs or symptoms ≤30 days

≤ Signs or symptoms <=30 days

Signs or symptoms >30 days

Signs or symptoms >30 days

Signs or symptoms >30 days

Second Test

IgG Western Blot ONLY

Second Test

IgG Western Blot ONLY

Second Test

Second Test

IgG Western Blot ONLY