Subacute Cutaneous Lupus Erythematosus (SCLE) tends to be less severe than SLE and rarely progresses to renal or CNS involvement.
SCLE is characterized by photodistributed erythematous lesions that are nonscarring.
SCLE occurs most commonly in young and middle-aged white women.
Patients may have some of the American Rheumatologic Association criteria for SLE, but serious disease with renal involvement is uncommon.
The eruption is typically papulosquamous and often closely resembles psoriasis or pityriasis rosea.
Lesions are often annular and heal without scarring (Fig. 34.21).
Sjögren syndrome, idiopathic thrombocytopenic purpura, urticarial vasculitis, and morphea have been reported in association with SCLE.
Lesions most often occur on the upper trunk, the V of the neck, and the extensor surfaces of the arms and hands.
Sjögren anti-SS-A (anti-Ro) and anti-SS-B (anti-La) antibodies are often found, although the absence of these antibodies does not exclude the diagnosis.