Explain that the patch consists of several layers. The layer closest to his skin contains a small amount of the drug and allows prompt drug introduction into the bloodstream. The next layer controls drug release from the main portion of the patch. The third layer contains the main dose. The outermost layer consists of an aluminized polyester barrier.

Teach the patient to apply the patch to the upper arm or chest and behind the ear. Warn him to avoid touching the gel or surrounding tape. Tell him to use a different site for each application to avoid skin irritation. If necessary, he can clip the hair at the site. Tell him to avoid any area that may cause uneven absorption, such as skin folds, scars, and calluses or any irritated or damaged skin areas. Also, tell him not to apply the patch below the elbow or knee.

Instruct the patient to wash his hands after application to remove any medication that may have rubbed off.

Warn the patient not to get the patch wet. Tell him to discard it if it leaks or falls off and then to clean the site and apply a new patch at a different site.

Instruct the patient to apply the patch at the same time at the prescribed interval. Bedtime application is ideal because body movement is reduced during the night. Finally, tell him to apply a new patch about 30 minutes before removing the old one.

The patient must remove the old patch so he does not get a cumulative drug effect.