Contraindicated in:
Use Cautiously in:
50 mL/min)CNS: confusion, dizziness, drowsiness, hallucinations, headache.
CV: ARRHYTHMIAS.
GI: constipation, diarrhea, drug-induced hepatitis, nausea.
GU: ↓sperm count, erectile dysfunction.
Endo: gynecomastia.
Hemat: AGRANULOCYTOSIS, APLASTIC ANEMIA, anemia, neutropenia, thrombocytopenia.
Misc: hypersensivity reactions.
(Generic available)
Renal Impairment
Absorption: 70–95% absorbed after oral administration.
Distribution: Enters breast milk and cerebrospinal fluid.
Metabolism/Excretion: 60% excreted unchanged by the kidneys; some hepatic metabolism; at least 1 metabolite has histamine blocking activity.
Half-life: 1.6 hr.
NDC Code*
