Contraindicated in:
Use Cautiously in:
EENT: optic neuritis.
GI: abdominal pain, anorexia, HEPATITIS, nausea, vomiting.
Metab: hyperuricemia.
MS: joint pain.
Neuro: confusion, dizziness, hallucinations, headache, malaise, peripheral neuritis.
Resp: pulmonary infiltrates.
Misc: anaphylactoid reactions, fever.
Drug-Drug:
Absorption: Rapidly and well absorbed (80%) from the GI tract.
Distribution: Widely distributed; crosses blood-brain barrier in small amounts.
Metabolism/Excretion: 50% metabolized by the liver, 50% eliminated unchanged by the kidneys.
Half-life: 3.3 hr (↑ in renal or hepatic impairment).
NDC Code*