Contraindicated in:
Use Cautiously in:
CV: angina, MI, peripheral edema.
Derm: hot flashes, rash, sweating.
EENT: pharyngitis.
F and E: hypercalcemia.
GI: nausea, abdominal pain, anorexia, constipation, diarrhea, dry mouth, vomiting.
GU: ↓ fertility (females), pelvic pain, vaginal bleeding, vaginal dryness.
Metab: ↑ weight, hypercholesterolemia.
MS: back pain, arthritis, bone pain, carpal tunnel syndrome, fracture, myalgia.
Neuro: headache, weakness, dizziness., paresthesia.
Resp: cough, dyspnea.
Misc: pain, HYPERSENSITIVITY REACTIONS (INCLUDING ANAPHYLAXIS AND ANGIOEDEMA) .
Absorption: 8385% absorbed following oral administration.
Distribution: Unknown.
Metabolism/Excretion: 85% metabolized by the liver; 11% excreted renally.
Half-life: 50 hr.
(lowering of serum estradiol)
ROUTE | ONSET | PEAK | DURATION |
---|---|---|---|
PO | within 24 hr | 14 days | 6 days |
Following cessation of therapy.
NDC Code*