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Indications

High Alert

Contraind./Precautions

Contraindicated in:

Use Cautiously in:

Adv. Reactions/Side Effects

Related to hyperphosphatemia, unless otherwise indicated

CV: ARRHYTHMIAS, CARDIAC ARREST, ECG changes (absent P waves, widening of the QRS complex with biphasic curve), hypotension.
hyperkalemia: ARRHYTHMIAS, ECG changes (prolonged PR interval, ST segment depression, tall-tented T waves).

GI: diarrhea, abdominal pain, nausea, vomiting.

F and E: hyperkalemia, hyperphosphatemia, hypocalcemia, hypomagnesemia.

Local: irritation at IV site, phlebitis.

MS: hyperkalemia: muscle cramps; hypercalcemia: tremors.

Neuro: flaccid paralysis, heaviness of legs, paresthesias , confusion, listlessness, weakness.

Interactions

Drug-Drug:

Drug-Food:

Availability

(Generic available)

Monobasic Potassium Phosphate

Potassium Phosphate and Sodium Phosphate

Potassium Phosphate

Route/Dosage

Monobasic Potassium Phosphate

Potassium Phosphate and Sodium Phosphate

Potassium Phosphate

US Brand Names

monobasic potassium phosphate: K-Phos

Potassium Phosphate and Sodium Phosphate: K-Phos Neutral

Action

Therapeutic Effects:

Classifications

Therapeutic Classification: antiurolithics, mineral and electrolyte replacements/supplements

Pharmacokinetics

Absorption: Well absorbed following oral administration. Vitamin D promotes GI absorption of phosphates.

Distribution: Phosphates enter extracellular fluids and are then actively transported to sites of action.

Metabolism/Excretion: Excreted mainly (>90%) by the kidneys.

Half-life: Unknown.

Time/Action Profile

(effects on serum phosphate levels)

ROUTEONSETPEAKDURATION
POunknownunknownunknown
IVrapid (min–hr)end of infusionunknown

Patient/Family Teaching

Pronunciation

poe-TASS-ee-um FOSS-fate audio

Code

NDC Code*