- PO (Adults): 225–400 mg/day in 3–4 divided doses.
- IV (Adults): 570 mcg/kg; maximum dose 60 mg.
Contraindicated in:
Use Cautiously in:
CV: hypotension, arrhythmias, flushing.
IV only: MI.
GI: nausea, diarrhea, GI upset, vomiting.
Derm: rash.
Neuro: dizziness, headache, syncope.
IV only: transient cerebral ischemia, weakness.
Resp: IV only: bronchospasm.
Drug-Drug:
(Generic available)
Therapeutic Classification: antiplatelet agents, diagnostic agents (coronary vasodilators)
Pharmacologic Classification: platelet adhesion inhibitors
Absorption: Moderately absorbed (30–60%) after oral administration. IV administration results in complete bioavailability.
Distribution: Widely distributed to tissues.
Metabolism/Excretion: Metabolized by the liver; excreted in the bile.
Half-life: 10 hr.
(PO = antiplatelet activity, IV = coronary vasodilation)
| ROUTE | ONSET | PEAK | DURATION |
|---|---|---|---|
| PO | unknown | unknown | unknown |
| IV | unknown | 6.5 min† | 30 min |
†From start of infusion.
NDC Code*
