Contraindicated in:
Use Cautiously in:
Related to hyperphosphatemia, unless otherwise indicated
CNS: confusion, listlessness, weakness.
CV: ARRHYTHMIAS, CARDIAC ARREST, ECG changes (absent P waves, widening of the QRS complex with biphasic curve), hypotension.
hyperkalemia: ARRHYTHMIAS, bradycardia, ECG changes (prolonged PR interval, ST segment depression, peaked T waves).
GI: abdominal pain, diarrhea, flatulence, nausea, vomiting.
F and E: hyperkalemia, hyperphosphatemia, hypocalcemia, hypomagnesemia.
MS: muscle cramps, tremors.
Neuro: flaccid paralysis, heaviness of legs, paresthesias.
Drug-Drug:
Drug-Food:
Absorption: Well absorbed following oral administration.
Distribution: Phosphates enter extracellular fluids and are then actively transported to sites of action.
Metabolism/Excretion: Excreted mainly (>90%) by the kidneys.
Half-life: Unknown.